Results 41 to 50 of about 476,060 (306)

Recombining the structures of HIV integrase, RuvC and RNase H [PDF]

open access: yesStructure, 1995
The recently reported crystal structures of two recombination enzymes, the catalytic domain of HIV integrase and Escherichia coli RuvC, an endonuclease, are surprisingly similar to that of ribonuclease H suggesting the possibility that they have a common enzymatic mechanism.
Thomas A. Steitz, Wei Yang
openaire   +3 more sources

The third positive element in the greedy $B_h$-set [PDF]

open access: yesPalestine Journal of Mathematics 14 (2025), 213--216, 2023
For $h \geq 1$, a $B_h$-set is a set of integers such that every integer $n$ has at most one representation in the form $n = a_{i_1} + \cdots + a_{i_h}$, where $a_{i_j} \in A$ for all $j = 1,\ldots, h$ and $a_{i_1} \leq \ldots \leq a_{i_h}$.
arxiv  

The fourth positive element in the greedy $B_h$-set [PDF]

open access: yesJournal of Integer Sequences 27 (2024), Article 24.7.3, pp. 1--10, 2023
For $h \geq 1$, a $B_h$-set is a set of integers such that every integer $n$ has at most one representation in the form $n = a_{i_1} + \cdots + a_{i_h}$, where $a_{i_r} \in A$ for all $r = 1,\ldots, h$ and $a_{i_1} \leq \ldots \leq a_{i_h}$.
arxiv  

The RNase J-Based RNA Degradosome Is Compartmentalized in the Gastric Pathogen Helicobacter pylori

open access: yesmBio, 2020
Posttranscriptional regulation is a major level of gene expression control in any cell. In bacteria, multiprotein machines called RNA degradosomes are central for RNA processing and degradation, and some were reported to be compartmentalized inside these
Alejandro Tejada-Arranz   +5 more
doaj   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Efficient and specific DNA oligonucleotide rRNA probe-based rRNA removal in Talaromyces marneffei

open access: yesMycology, 2022
Emerging evidence showed that lncRNAs play important roles in a wide range of biological processes of fungi such as Saccharomyces cerevisiae. However, systemic identification of lncRNAs in non-model fungi is a challenging task as the efficiency of rRNA ...
Xueyan Hu   +3 more
doaj   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

In Vitro Anti-HIV-1 Reverse Transcriptase and Integrase Properties of Punica granatum L. Leaves, Bark, and Peel Extracts and Their Main Compounds

open access: yesPlants, 2021
In a search for natural compounds with anti-HIV-1 activity, we studied the effect of the ethanolic extract obtained from leaves, bark, and peels of Punica granatum L.
Cinzia Sanna   +8 more
doaj   +1 more source

Differential roles of the RNases H in preventing chromosome instability [PDF]

open access: yesProceedings of the National Academy of Sciences, 2016
Significance DNA damage can lead to chromosome instability and loss of genetic information, resulting in cell death or diseases such as cancer. One source of damage is DNA:RNA hybrids that form when RNA transcripts hybridize to homologous sequences in the genome.
Zimmer, Anjali D, Koshland, Douglas
openaire   +4 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy