Results 121 to 130 of about 18,946,844 (347)
, 2012 ATP binding cassette proteins are a large and diverse family of molecular machines and include transmembrane transporter, chromosome maintenance and DNA repair proteins, and translation factors.
Karl-Peter Hopfner, Roy
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Inhibition of Eukaryotic RNase P [PDF]
Biophysical Journal, 2010 Ribonuclease P (RNase P) is an essential RNA enzyme found in all phylogenetic domains that is best known for catalyzing the 5’ endonucleolytic cleavage of precursor transfer RNAs (pre-tRNAs). In bacteria, the enzyme consists of a single, catalytic RNA subunit and one small protein, while the archaeal and eukaryotic enzymes have 4-10 proteins in ...
Marvin, Michael C. +2 more
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
BMC Microbiology, 2012 Background Ribonuclease R (RNase R) is an exoribonuclease that recognizes and degrades a wide range of RNA molecules. It is a stress-induced protein shown to be important for the establishment of virulence in several pathogenic bacteria. RNase R has also
Moreira Ricardo N +4 more
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Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]
, 2013 OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes. While RprA activates rpoS for translation, OxyS
Callaghan, Anastasia +9 more
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Introduction. RNase MRP/RNase P systems - [PDF]
, 1996 Contains fulltext : 29698___.PDF (Publisher’s version ) (Open Access)
Karwan, R., Pluk, H., Venrooij, W.J. van
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IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, 2019 The mature 5′‐ends of tRNAs are generated by RNase P in all domains of life. The ancient form of the enzyme is a ribonucleoprotein consisting of a catalytic RNA and one or more protein subunits.
T. S. Schwarz +6 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Viruses, 2014 RNase P ribozyme can be engineered to be a sequence-specific gene-targeting agent with promising application in both basic research and clinical settings.
Zhu Yang +7 more
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Purification and Biophysical Study of RNase P Proteins 21 and 29 from Methanocaldococcus jannaschii [PDF]
, 2010 RNase P is an endonuclease with a rare catalytic RNA core. The enzyme is a ribonucleoprotein (RNP) complex and is primarily responsible for cleaving the 5’ RNA leader sequence from precursor tRNA (ptRNA) molecules. The maturation of tRNA is necessary for
Smith, David
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