Results 141 to 150 of about 430,076 (284)

Transcript Identification Using Arrayed Hydrogels With TrapFISH

Advanced Materials Technologies, EarlyView.
TrapFISH is a novel method for high‐throughput single‐cell transcriptomics. It embeds cells in hyaluronic acid hydrogel beads and uses probe hybridization to quantify custom gene panels. By arraying hydrogels in microfluidic devices, cell barcoding is removed, enhancing scalability for studying cellular heterogeneity and rare cell states by targeting ...
David B. Morse, Zenon Toprakcioglu, Akhila Denduluri‐Marthi, James D. Brenton, Craig J. Thomas, Tuomas P. J. Knowles   +5 more
wiley   +1 more source

Identification of a precursor molecular for the RNA moiety of the processing enzyme RNase P. [PDF]

, 1983
Michael Gurevitz, Swatantra Kumar Jain, David Apirion   +2 more
openalex   +1 more source

Cleavage kinetics of human mitochondrial RNase P and contribution of its non-nuclease subunits. [PDF]

Nucleic Acids Res, 2023
Vilardo E, Toth U, Hazisllari E, Hartmann RK, Rossmanith W.   +4 more
europepmc   +1 more source

Single‐Layer Radially Compartmentalized Paper Chip (RCP‐Chip) for Rapid Isothermal Multiplex Detection of SARS‐CoV‐2 Gene Targets

Advanced Sensor Research, EarlyView.
The single‐layer RCP‐Chip enables rapid, multiplexed detection of SARS‐CoV‐2 RNA using RT‐LAMP and gold nanoparticle‐enhanced colorimetric readouts. After sample loading, amplification occurs within radially arranged chambers, allowing simultaneous detection of E and N genes.
Pavithra Sukumar, Alla Saleh, Muhammedin Deliorman, Mohammad A. Qasaimeh   +3 more
wiley   +1 more source

Lead‐ion‐induced cleavage of RNase P RNA [PDF]

, 1994
Jerzy Ciesiołka, Wolf‐Dietrich Hardt, Judith Schlegl, Volker A. Erdmann, Roland K. Hartmann   +4 more
openalex   +1 more source

Recognition of tRNA^His in an RNase P-Free Nanoarchaeum. [PDF]

Microbiol Spectr, 2023
Ivanesthi IR, Rida GRN, Setiawibawa AA, Tseng YK, Muammar A, Wang CC.   +5 more
europepmc   +1 more source

Mimicking Biochemical Traits with a Synthetic Lipid Nanoparticles SARS‐COV‐2 Model

Advanced Therapeutics, Volume 8, Issue 6, June 2025.
A synthetic virus model developed using lipid nanoparticles, which incorporate encapsulated mRNA and nucleocapsid (N) protein along with surface‐conjugated spike (S) protein, mimics the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), allowing for the advancement of diagnostic product assessment.
Ignasia Handipta Mahardika, Hyun Park, Eunjin Huh, Changyoon Baek, Shin‐Gyu Cho, Kwang‐Hwan Jung, Junhong Min, Kwanwoo Shin   +7 more
wiley   +1 more source

The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. [PDF]

, 1994
Zoi Lygerou, Philip Mitchell, E Petfalski, Bertrand Séraphin, David Tollervey   +4 more
openalex   +1 more source

Chloroplast ribonuclease P does not utilize the ribozyme-type pre-tRNA cleavage mechanism. [PDF]

, 2015
This is the published version. Copyright 2000 by the RNA Society.The transfer RNA 5' maturation enzyme RNase P has been characterized in Bacteria, Archaea, and Eukarya.
Gegenheimer, Peter Albert, Li, Xinqiang, Thomas, Brian C.   +2 more
core  

Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors

Advanced Therapeutics, Volume 8, Issue 6, June 2025.
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe, Jacobus Burger, Jamie Jones, Apurva Panjla, William L. Murphy   +4 more
wiley   +1 more source