Results 141 to 150 of about 436,820 (281)

Nanoinjection Platform for Drug Delivery in Breast Cancer Therapeutics

Advanced Materials Interfaces, EarlyView.
A schematic shows Nanoarchaeosomes loaded with doxorubicin (NAD) delivered via silicon nanotubes (SiNTs) into MCF‐7 cells, triggering apoptosis and necrosis. Released doxorubicin generates ROS, disrupts mitochondria, and intercalates DNA. This dual‐action nanoinjection enhances cytotoxicity and improves breast cancer therapy efficacy.
Kaviya Vijayalakshmi Babunagappan, Subastri Ariraman, Jann Harberts, Vimalraj Selvaraj, Mukilarasi Bedatham, Narendran Sekar, Nicolas H Voelcker, Roey Elnathan, Swathi Sudhakar   +8 more
wiley   +1 more source

Suppressing Kaposi's Sarcoma-Associated Herpesvirus Lytic Gene Expression and Replication by RNase P Ribozyme. [PDF]

Molecules, 2023
Liu Y, Chen YC, Yan B, Liu F.
europepmc   +1 more source

Transcript Identification Using Arrayed Hydrogels With TrapFISH

Advanced Materials Technologies, EarlyView.
TrapFISH is a novel method for high‐throughput single‐cell transcriptomics. It embeds cells in hyaluronic acid hydrogel beads and uses probe hybridization to quantify custom gene panels. By arraying hydrogels in microfluidic devices, cell barcoding is removed, enhancing scalability for studying cellular heterogeneity and rare cell states by targeting ...
David B. Morse, Zenon Toprakcioglu, Akhila Denduluri‐Marthi, James D. Brenton, Craig J. Thomas, Tuomas P. J. Knowles   +5 more
wiley   +1 more source

Bacterial RNA-free RNase P: Structural and functional characterization of multiple oligomeric forms of a minimal protein-only ribonuclease P. [PDF]

J Biol Chem, 2023
Wilhelm CA, Mallik L, Kelly AL, Brotzman S, Mendoza J, Anders AG, Leskaj S, Castillo C, Ruotolo BT, Cianfrocco MA, Koutmos M.   +10 more
europepmc   +1 more source

Sequence and functional characterization of RNase P RNA from the chl a/b containing cyanobacterium Prochlorothrix hollandica [PDF]

, 1998
Christiane Fingerhut, Astrid Schön
openalex   +1 more source

Nanomaterial‐Based Optical Biosensors for SARS‐CoV‐2 Detection: A Retrospective of the Pandemic

Advanced Sensor Research, EarlyView.
This review discusses nanomaterial‐based optical biosensors developed for or adapted to the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). It concludes by providing a perspective on how lessons learned during the coronavirus disease of 2019 (COVID‐19) pandemic may be applied for future research on nanomaterial‐based ...
Flavie Martin, Scott G. Harroun, Michel Meunier   +2 more
wiley   +1 more source

The recognition by RNase P of precursor tRNAs.

, 1988
Madeline F. Baer, R M Reilly, George M. McCorkle, T Hai, Sidney Altman, Uttam L. RajBhandary   +5 more
openalex   +1 more source

Cleavage by RNase P of Gene N mRNA Reduces Bacteriophage Burst Size [PDF]

, 1996
Y. Li, Sidney Altman
openalex   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Gambogic acid and juglone inhibit RNase P through distinct mechanisms. [PDF]

J Biol Chem, 2022
Wu Meyers N, Karasik A, Kaitany K, Fierke CA, Koutmos M.   +4 more
europepmc   +1 more source