Results 171 to 180 of about 436,820 (281)

Structure-function analysis in nuclear RNase P RNA [PDF]

, 1996
David R. Engelke, Eileen Pag�n-Ramos, Anthony J. Tranguch   +2 more
openalex   +1 more source

Tumor‐Associated Sympathetic Nerves Promote the Progression of Epstein‐Barr Virus‐Positive Diffuse Large B‐Cell Lymphoma

Advanced Science, EarlyView.
Sympathetic nerve innervation promotes the progression of Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma (EBV+ DLBCL) via β2‐adrenergic receptors. The discovery of enhanced nerve infiltration and β2AR expression reveals a novel mechanism and highlights the sympathetic–β2AR axis as a promising target for therapeutic intervention in EBV+ DLBCL.
Silan Huang, Dexin Lei, Linbin Yang, Aiwei Bi, Yanlou Wang, Peng Zhang, Dongyu Zhuang, Honglian Liu, Qingqing Cai, Man Nie, Yi Xia   +10 more
wiley   +1 more source

Synthetic riboswitches for the analysis of tRNA processing by eukaryotic RNase P enzymes. [PDF]

RNA, 2022
Ender A, Grafl N, Kolberg T, Findeiß S, Stadler PF, Mörl M.   +5 more
europepmc   +1 more source

Solution structure and metal-ion binding of the P4 element from bacterial RNase P RNA [PDF]

, 2000
M. Lienhard Schmitz, Ignacio Tinoco
openalex   +1 more source

Revealing Cell‐Free Mitochondrial DNA Breakage Patterns as Novel Biomarkers for Sepsis

Advanced Science, EarlyView.
Uncovering distinct plasma cfmtDNA breakage patterns opens new frontiers for early sepsis detection and prognosis. Unique cleavage hotspots in RNR2 and COX2 regions outperform traditional biomarkers, while mechanistic insights suggest bacterial endonuclease involvement.
Haitang Liao, Ruiyan Ma, Shuai Hao, Xuxin Tan, Xue Zeng, Rui Song, Bing Chen, Zhezhe Cao, Wei Shen, Zhenchun Luo, Jianfeng Huang, He Huang, Liangming Liu, Chenyang Duan   +13 more
wiley   +1 more source

Active site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3'-S-phosphorothiolate internucleotide linkage [PDF]

, 2000
Jens M. Warnecke, Erik J. Sontheimer, Joseph A. Piccirilli, R.K. Hartmann   +3 more
openalex   +1 more source

piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization

Advanced Science, EarlyView.
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang, Fan Li, Yudong Lin, Zeyi Lu, Wenqin Luo, Zhehao Xu, Ziwei Zhu, Yi Lu, Xudong Mao, Yang Li, Zhinian Shen, Haohua Lu, Yining Chen, Liqun Xia, Mingchao Wang, Lifeng Ding, Gonghui Li   +16 more
wiley   +1 more source

Structural basis of RNA processing by human mitochondrial RNase P. [PDF]

Nat Struct Mol Biol, 2021
Bhatta A, Dienemann C, Cramer P, Hillen HS.   +3 more
europepmc   +1 more source

Comparative structural analysis of nuclear RNase P RNAs from yeast

, 1993
Anthony J. Tranguch, David R. Engelke
openalex   +1 more source

The 3′ substrate determinants for the catalytic efficiency of the Bacillus subtilis RNase P holoenzyme suggest autolytic processing of the RNase P RNA in vivo [PDF]

, 2000
Andrew Loria, Tao Pan
openalex   +1 more source