Results 171 to 180 of about 18,946,844 (347)

Sequence Characterization and Spatiotemporal Expression Patterns of PbS26-RNase Gene in Chinese White Pear (Pyrus bretschneideri)

The Scientific World Journal, 2014
Many flowering plants exhibit an important intraspecific reproductive barrier phenomenon, that is, self-incompatibility (SI), in which S-RNase genes play a significant role.
Lin Zhang, Baoguang Jia, Feng Zou, Xiaofeng Tan, Min Liu, Zhibo Song, Yanling Zeng, Nan Jiang, Deyi Yuan   +8 more
doaj   +1 more source

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

Bi-allelic variants in the mitochondrial RNase P subunit PRORP cause mitochondrial tRNA processing defects and pleiotropic multisystem presentations

American Journal of Human Genetics, 2021
I. Hochberg, L. A. Demain, J. Richer, K. Thompson, J. Urquhart, A. Rea, W. Pagarkar, Agustí Rodríguez-Palmero, A. Schlüter, E. Verdura, A. Pujol, P. Quijada-Fraile, A. Amberger, A. Deutschmann, Sandra Demetz, Meredith K. Gillespie, I. Belyantseva, H. McMillan, M. Barzik, G. Beaman, Reeya Motha, Kah Ying Ng, J. O’Sullivan, S. Williams, S. Bhaskar, I. Lawrence, E. Jenkinson, J. Zambonin, Z. Blumenfeld, S. Yalonetsky, S. Oerum, W. Rossmanith, W. Yue, J. Zschocke, K. Munro, B. Battersby, T. Friedman, Robert W. Taylor, R. O’Keefe, W. Newman   +39 more
semanticscholar   +1 more source

Inhibition of gene expression by RNase P

New Biotechnology, 2010
The ability to interfere with gene expression is of crucial importance to unravel the function of genes and is also a promising therapeutic strategy. Here we discuss methodologies for inhibition of target RNAs based on the cleavage activity of the essential enzyme, Ribonuclease P (RNase P).
Eirik Wasmuth, Lundblad, Sidney, Altman
openaire   +2 more sources

Intrinsically Disordered Protein‐Inspired Nanovector‐Based Coacervates for the Direct Cytosolic Transport of Biomacromolecules

Advanced Materials, EarlyView.
Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin, Hyemin Park, Seuk‐Min Ryu, Dagyeong Guk, Jaeeun Lee, Seongeon Jin, Changjoon Keum, Jinyoung Park, Myoung‐Hwan Park, Chaekyu Kim, Hojun Kim, Jaegeun Noh, Kwan Hyi Lee, Ja‐Hyoung Ryu, Youngdo Jeong   +14 more
wiley   +1 more source

Endogenous Ribonucleases: Therapeutic Targeting of the Transcriptome Through Oligonucleotide-Triggered RNA Inactivation

Biomolecules
The selective regulation of gene expression at the RNA level represents a rapidly evolving field offering substantial clinical potential. This review examines the molecular mechanisms of intracellular enzymatic systems that utilize single-stranded ...
Daria A. Chiglintseva, Olga A. Patutina, Marina A. Zenkova   +2 more
doaj   +1 more source

Ribonuclease (RNase) Prolongs Survival of Grafts in Experimental Heart Transplantation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundCell damage, tissue and vascular injury are associated with the exposure and release of intracellular components such as RNA, which promote inflammatory reactions and thrombosis. Based on the counteracting anti‐inflammatory and cardioprotective
Eike Kleinert, Martin C. Langenmayer, Bruno Reichart, Jana Kindermann, Barbara Griemert, Andreas Blutke, Kerstin Troidl, Tanja Mayr, Tobias Grantzow, Fatih Noyan, Jan‐Michael Abicht, Silvia Fischer, Klaus T. Preissner, Ruediger Wanke, Elisabeth Deindl, Sonja Guethoff   +15 more
doaj   +1 more source

Eukaryotic RNase P [PDF]

Molecular Cell, 2003
Mann, Hagit, Ben-Asouli, Yitzhak, Schein, Aleks, Moussa, Sana, Jarrous, Nayef   +4 more
openaire   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

RNase P ribozyme inhibits cytomegalovirus replication by blocking the expression of viral capsid proteins [PDF]

, 2004
Kyong‐Tai Kim
openalex   +1 more source