Results 21 to 30 of about 20,593,893 (291)
Potential Applications of RNase P Ribozyme Against Hepatitis B Virus [PDF]
MoleculesNucleic acid-based gene-interfering molecules, such as antisense oligonucleotides, ribozymes, and small interfering RNA (siRNA), represent exciting gene-targeting agents for therapeutic applications.
Thomas Sorrell, Yujun Liu, Fenyong Liu
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hPop5, a Protein Subunit of the Human RNase MRP and RNase P Endoribonucleases [PDF]
Journal of Biological Chemistry, 2001 The RNase MRP and RNase P particles both function as endoribonucleases. RNase MRP has been implicated in the processing of precursor-rRNA, whereas RNase P has been shown to function in the processing of pre-tRNA. Both ribonucleoprotein particles have an RNA component that can be folded into a similar secondary structure and share several protein ...
Eenennaam, H. van +4 more
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The DnaJK chaperone of Bacillus subtilis post-transcriptionally regulates gene expression through the YlxR(RnpM)/RNase P complex [PDF]
mBioTo survive in harsh natural environments, translation and mRNA metabolism must be tightly and coordinately controlled, as saving biological costs increases fitness. However, the roles of protein chaperones in this control system are unclear.
Mitsuo Ogura +3 more
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Pop3p is essential for the activity of the RNase MRP and RNase P ribonucleoproteins invivo
EMBO Journal, 1997 RNase MRP is a ribonucleoprotein (RNP) particle which is involved in the processing of pre-rRNA at site A3 in internal transcribed spacer 1. Although RNase MRP has been analysed functionally, the structure and composition of the particle are not well characterized.
David Tollervey
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Difference between Mitochondrial RNase P and Nuclear RNase P [Letters to the Editor] [PDF]
, 2001 Copyright © 2001 by the American Society for Microbiology.
Rossmanith, Walter +3 more
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RNA Biology, 2009 Ribonuclease P (RNase P) is a ribonucleoprotein comprised of a catalytic RNA subunit and one or several protein subunits. RNase P is best known for its role in 5'-processing of tRNA precursors. RNase P enzymes from almost all forms of life, including protein-synthesizing organelles, contain an RNase P with a conserved, homologous RNA.
J Christopher, Ellis, James W, Brown
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A novel experimental approach for the selective isolation and characterization of human RNase MRP
RNA Biology, 2022 RNase MRP is a ribonucleoprotein complex involved in the endoribonucleolytic cleavage of different RNAs. Mutations in the RNA component of the RNP are the cause of cartilage hair hypoplasia.
Merel Derksen +5 more
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The evolution of RNase P [PDF]
RNA, 2015 Article and publication date are at http://www.rnajournal.org/cgi/doi/10.1261/rna.050732.115. Freely available online through the RNA Open Access option.
Engelke, David R., Fierke, Carol A.
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Silencing Antibiotic Resistance with Antisense Oligonucleotides
Biomedicines, 2021 Antisense technologies consist of the utilization of oligonucleotides or oligonucleotide analogs to interfere with undesirable biological processes, commonly through inhibition of expression of selected genes.
Saumya Jani +2 more
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Difference between Mitochondrial RNase P and Nuclear RNase P [PDF]
Molecular and Cellular Biology, 2001 We previously demonstrated that mammalian cells contain at least two distinct RNase P activities, one nuclear and one mitochondrial (5, 7). These enzymes were shown to have different substrate specificities and distinct molecular and enzymatic properties (5–7).
Walter Rossmanith, Thomas Potuschak
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