Results 21 to 30 of about 25,923,055 (288)
Is alba an RNase P subunit? [PDF]
RNA Biology, 2007 It has been suggested that Alba, a well-established chromatin protein in Archaea, is also a subunit of the archaeal RNase P holoenzyme, based on the observation that the homolog of this protein in humans has been shown to be associated with RNase P activity.
J Chris, Ellis +2 more
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Difference between Mitochondrial RNase P and Nuclear RNase P [PDF]
Molecular and Cellular Biology, 2001 We previously demonstrated that mammalian cells contain at least two distinct RNase P activities, one nuclear and one mitochondrial (5, 7). These enzymes were shown to have different substrate specificities and distinct molecular and enzymatic properties (5–7).
Walter Rossmanith, Thomas Potuschak
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Function and assembly of a chromatin-associated RNase P that is required for efficient transcription by RNA polymerase I. [PDF]
PLoS ONE, 2008 Human RNase P has been initially described as a tRNA processing enzyme, consisting of H1 RNA and at least ten distinct protein subunits. Recent findings, however, indicate that this catalytic ribonucleoprotein is also required for transcription of small ...
Robert Reiner +3 more
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The catalytic core of RNase P [PDF]
Nucleic Acids Research, 1996 A deletion mutant of the catalytic RNA component of Escherichia coli RNase P missing residues 87-241 retains the ability to interact with the protein component to form a functional catalyst. The deletion of this phylogenetically conserved region significantly increases the Km, indicating that the deleted structures may be important for binding to the ...
C J, Green, R, Rivera-León, B S, Vold
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Crystallization and crystallographic analysis of an Arabidopsis nuclear proteinaceous RNase P [PDF]
, 2015 RNase P activity is ubiquitous and involves the 5' maturation of precursor tRNAs. For a long time, it was thought that all RNases P were ribonucleoproteic enzymes.
Giegé, Philippe +8 more
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Zebrafish RNase T2 genes and the evolution of secretory ribonucleases in animals
BMC Evolutionary Biology, 2009 Background Members of the Ribonuclease (RNase) T2 family are common models for enzymological studies, and their evolution has been well characterized in plants.
Essner Jeffrey J +5 more
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Evolution of ribonuclease H genes in prokaryotes to avoid inheritance of redundant genes
BMC Evolutionary Biology, 2007 Background A theoretical model of genetic redundancy has proposed that the fates of redundant genes depend on the degree of functional redundancy, and that functionally redundant genes will not be inherited together.
Tomita Masaru +2 more
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Architecture and Function of the Human Endonucleases RNase P and RNase MRP [PDF]
IUBMB Life, 2000 AbstractIn the past decade, important advances have been made in our knowledge of the composition of human RNase MRP and RNase P complexes. Both ribonucleoprotein particles function as endonucleases and contain RNA components that are structurally related.
Eenennaam, H. van +3 more
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Genetic diversity of human RNase 8
BMC Genomics, 2012 Background Ribonuclease 8 is a member of the RNase A family of secretory ribonucleases; orthologs of this gene have been found only in primate genomes. RNase 8 is a divergent paralog of RNase 7, which is lysine-enriched, highly conserved, has prominent ...
Chan Calvin C +4 more
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P finder: genomic and metagenomic annotation of RNase P RNA gene (rnpB)
BMC Genomics, 2020 Background The rnpB gene encodes for an essential catalytic RNA (RNase P). Like other essential RNAs, RNase P’s sequence is highly variable. However, unlike other essential RNAs (i.e.
J. Christopher Ellis
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