Results 51 to 60 of about 1,790,411 (298)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Influence of a Reflective Identity Leadership Intervention on Perceived Identity Leadership, Social Identity, and Psychological Safety in Cricket

Behavioral Sciences
The purpose of this study was to investigate the influence of an identity leadership-framed reflective practice intervention on perceptions of leadership, social identity, and psychological safety in cricket.
Adam Hoult, Paul Mansell, Matthew J. Slater   +2 more
doaj   +1 more source

Performance Analysis of Industrial-Waste-Based Artificial Aggregates: CO₂ Uptake and Applications in Bituminous Pavement

Buildings, 2023
In order to raise the utilization rate of industrial waste and mitigate issues involving land resource occupation and environmental damage, in this study, industrial-waste-based artificial aggregates (IWAAs) were fabricated using steel slag powders, fly ...
Jian Ma, Xiaodong Wang, Zhen Zhang, Guangjian Dai, Yifei Huo, Yunfeng Zhao   +5 more
doaj   +1 more source

Distantly Supervised Road Segmentation

, 2017
We present an approach for road segmentation that only requires image-level annotations at training time. We leverage distant supervision, which allows us to train our model using images that are different from the target domain.
Kerola, Tommi, Saito, Shunta, Tsutsui, Satoshi   +2 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Evaluation of road performance and micro-mechanism analysis of bentonite plastic concrete subgrade

Materials Research Express
This study evaluated the performance of bentonite plasticized concrete with good deformation coordination as a road base material, to address the poor deformation coordination of rigid base layers in roads.
Zhang Guoming, Liang Xiaolin, Zhang Zenghui, Zhu Xincong, Lv Min, Bao Guiyong, Yang Jiacai   +6 more
doaj   +1 more source

The recycling of construction waste asphalt mixes – study case [PDF]

Archives of Civil Engineering
Construction waste (CW) has become one of the main factors exacerbating regional environmental damage, and how to recycle and utilize CW as a resource is also a key focus of future urban construction in China.
Mengya Jiang, Xiaoqing Cai
doaj   +1 more source

Experimental Study on the Road Performance of Phosphogypsum-Modified Lime-Fly Ash Stabilized Red Clay

Applied Sciences, 2023
To assess the impact of solid waste phosphogypsum on the road performance of lime-fly ash-stabilized red clay, we conducted comprehensive tests on the road performance, swelling and shrinkage characteristics, and mechanical properties of lime-fly ash ...
Shibin Huang, Yanzhou Ma, Jiaquan Wang, Zhinan Lin, Tianxin Chen   +4 more
doaj   +1 more source

Uncertainty-dependent data collection in vehicular sensor networks

, 2012
Vehicular sensor networks (VSNs) are built on top of vehicular ad-hoc networks (VANETs) by equipping vehicles with sensing devices. These new technologies create a huge opportunity to extend the sensing capabilities of the existing road traffic control ...
Płaczek, Bartłomiej
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source