Results 61 to 70 of about 2,324,507 (326)

Resampled Efficient Frontier Integration for MOEAs

Entropy, 2021
Mean-variance portfolio optimization is subject to estimation errors for asset returns and covariances. The search for robust solutions has been traditionally tackled using resampling strategies that offer alternatives to reference sets of returns or ...
David Quintana, David Moreno
doaj   +1 more source

Comparative and qualitative robustness for law-invariant risk measures

, 2014
When estimating the risk of a P&L from historical data or Monte Carlo simulation, the robustness of the estimate is important. We argue here that Hampel's classical notion of qualitative robustness is not suitable for risk measurement and we propose and ...
Krätschmer, Volker, Schied, Alexander, Zähle, Henryk   +2 more
core   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Dentz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Individualized microbiotas dictate the impact of dietary fiber on colitis sensitivity

Microbiome
Background The observation that the intestinal microbiota is  central in the development of IBD suggests that dietary fiber, the microbiota’s primary source of nourishment, could play a central role in these diseases.
Erica Bonazzi, Alexis Bretin, Lucile Vigué, Fuhua Hao, Andrew D. Patterson, Andrew T. Gewirtz, Benoit Chassaing   +6 more
doaj   +1 more source

One-Layer vs. Two-Layer SOM in the Context of Outlier Identification: A Simulation Study

Applied Sciences, 2021
In this work, we applied a stochastic simulation methodology to quantify the power of the detection of outlying mixture components of a stochastic model, when applying a reduced-dimension clustering technique such as Self-Organizing Maps (SOMs).
Gabriel Antonio Valverde Castilla, José Manuel Mira McWilliams, Beatriz González-Pérez   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Robust reliability or reliable robustness? : integrated consideration of robustness- and reliability-aspects

, 2015
Als zuverlässig bzw. robust werden im Allgemeinen Produkte oder Prozesse beschrieben, die den bestehenden Qualitätsanforderungen entsprechen. Gleichzeitig haben Definitionen aus dem Bereich Zuverlässigkeitstechnik und Robust Design allerdings keine grundlegende Übereinstimmung.
Kemmler, Stefan, Eifler, Tobias, Bertsche, Bernd, Howard, Thomas J.   +3 more
openaire   +3 more sources

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Robust Robustness

We propose a refinement of the maxmin approach to distributional robustness. A mechanism's payoff guarantee over an ambiguity set is robust if the guarantee is approximately satisfied at priors near the ambiguity set (in the weak topology). We show that many maxmin-optimal mechanisms in the literature give payoff guarantees that are not robust.
Ball, Ian, Kattwinkel, Deniz
openaire   +2 more sources

Robustness of Anytime Bandit Policies [PDF]

, 2011
This paper studies the deviations of the regret in a stochastic multi-armed bandit problem. When the total number of plays n is known beforehand by the agent, Audibert et al.
Audibert, Jean-Yves, Salomon, Antoine
core   +3 more sources