Results 31 to 40 of about 562,963 (309)
Molecular Systems Biology, 2008 Gene expression, like many biological processes, is subject to noise. This noise has been measured on a global scale, but its general importance to the fitness of an organism is unclear.
Ben Lehner
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EvoRSR: an integrated system for exploring evolution of RNA structural robustness
BMC Bioinformatics, 2009 Background Robustness, maintaining a constant phenotype despite perturbations, is a fundamental property of biological systems that is incorporated at various levels of biological complexity.
Ni Ming +4 more
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PERSPECTIVE: EVOLUTION AND DETECTION OF GENETIC ROBUSTNESS [PDF]
Evolution, 2003 Robustness is the invariance of phenotypes in the face of perturbation. The robustness of phenotypes appears at various levels of biological organization, including gene expression, protein folding, metabolic flux, physiological homeostasis, development, and even organismal fitness.
de Visser, J.A.G.M. +18 more
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Determinative developmental cell lineages are robust to cell deaths. [PDF]
PLoS Genetics, 2014 All forms of life are confronted with environmental and genetic perturbations, making phenotypic robustness an important characteristic of life. Although development has long been viewed as a key component of phenotypic robustness, the underlying ...
Jian-Rong Yang +2 more
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Idealised simulations of cyclones with robust symmetrically-unstable sting jets [PDF]
, 2020 Idealised simulations of Shapiro-Keyser cyclones developing a sting jet (SJ) are presented. Thanks to an improved and accurate implementation of thermal wind balance in the initial state, it has been possible to use more realistic environments than in ...
Clark, Peter A. +2 more
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Evolution of Robustness and Plasticity under Environmental Fluctuation: Formulation in terms of Phenotypic Variances [PDF]
, 2012 The characterization of plasticity, robustness, and evolvability, an important issue in biology, is studied in terms of phenotypic fluctuations. By numerically evolving gene regulatory networks, the proportionality between the phenotypic variances of ...
Kaneko, Kunihiko
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Upstream plasticity and downstream robustness in evolution of molecular networks
BMC Evolutionary Biology, 2004 Background Gene duplication followed by the functional divergence of the resulting pair of paralogous proteins is a major force shaping molecular networks in living organisms.
Eriksen Kasper +3 more
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Evolution of dominance in gene expression pattern associated with phenotypic robustness
BMC Ecology and Evolution, 2021 Background Mendelian inheritance is a fundamental law of genetics. When we consider two genomes in a diploid cell, a heterozygote’s phenotype is dominated by a particular homozygote according to the law of dominance.
Kenji Okubo, Kunihiko Kaneko
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Quantum computing of delocalization in small-world networks [PDF]
, 2005 We study a quantum small-world network with disorder and show that the system exhibits a delocalization transition. A quantum algorithm is built up which simulates the evolution operator of the model in a polynomial number of gates for exponential number
B. Georgeot +5 more
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Direct evolution of genetic robustness in microRNA [PDF]
Proceedings of the National Academy of Sciences, 2006 Genetic robustness, the invariance of the phenotype in the face of genetic perturbations, can endow the organism with reduced susceptibility to mutations. A large body of work in recent years has focused on the origins, mechanisms, and consequences of robustness in a wide range of biological systems.
Elhanan, Borenstein, Eytan, Ruppin
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