Rod monochromacy and the coevolution of cetacean retinal opsins. [PDF]
PLoS Genetics, 2013 Cetaceans have a long history of commitment to a fully aquatic lifestyle that extends back to the Eocene. Extant species have evolved a spectacular array of adaptations in conjunction with their deployment into a diverse array of aquatic habitats ...
Robert W Meredith +4 more
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Discovery and design of photocyclic animal opsins: potential application to gene therapy from non-visual opsin research [PDF]
Eye and VisionOpsins are universal photoreceptive proteins in animals. Rhodopsin is the best-studied opsin and functions as a visual sensor in rod cells of human and mouse retinas.
Takahiro Yamashita
doaj +2 more sources
Light intensity and opsin sensitivity shape the morphology of cone photoreceptor outer segments. [PDF]
PLoS BiologyRegulation of neural cell morphology remains a fundamental question in neuroscience. Photoreceptor cells, a specialized class of neurons capable of initiating the phototransduction cascade, exhibit distinct structural and morphological characteristics ...
Jingjin Xu +8 more
doaj +2 more sources
Two genes, one culprit - a functional candidate validation of a SPATA7 deletion in dogs with day blindness/retinal degeneration. [PDF]
PLoS GeneticsInherited retinal diseases (IRDs) are a diverse group of disorders that share common vision deficits ranging from early onset blindness to severe and progressive later-onset disease. We report a form of early-onset day-vision loss, cone-rod dystrophy, in
Leonardo Murgiano +13 more
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Syntaxin 3B Mediates Light‐Dependent Interactions with STXBP1 and Arrestin 4: Distinct Roles in Rods and Cones [PDF]
Advanced ScienceSyntaxin 3 (STX3), a member of the soluble N‐ethylmaleimide‐sensitive factor attachment protein receptor (SNARE) family, plays a central role in vesicle fusion.
Lars Tebbe +5 more
doaj +2 more sources
Vision using multiple distinct rod opsins in deep-sea fishes. [PDF]
Science, 2019 Musilova Z +17 more
europepmc +3 more sources
Frontiers in Marine Science, 2022 Visual photoreceptors in fish are usually adjusted to the light environment to ensure the highest efficiency and best adaptation. In the Senegalese sole, metamorphosis determines migration from pelagic to benthic habitats, with marked differences in both
Sara Frau +12 more
doaj +1 more source
Opsins as main regulators of skin biology
Journal of Photochemistry and Photobiology, 2023 Opsins are light-sensitive proteins that are found across the animal kingdom. In mammals, opsins are classically associated with image-forming processes, a function exerted by cone and rod opsins.
Ana Maria de Lauro Castrucci +2 more
doaj +1 more source
Spectral tuning and deactivation kinetics of marine mammal melanopsins
PLoS ONE, 2021 In mammals, the photopigment melanopsin (Opn4) is found in a subset of retinal ganglion cells that serve light detection for circadian photoentrainment and pupil constriction (i.e., mydriasis).
Jeffry I. Fasick +6 more
doaj +3 more sources
TMT-Opsins differentially modulate medaka brain function in a context-dependent manner.
PLoS Biology, 2021 Vertebrate behavior is strongly influenced by light. Light receptors, encoded by functional opsin proteins, are present inside the vertebrate brain and peripheral tissues.
Bruno M Fontinha +10 more
doaj +1 more source