The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control [PDF]
Human Molecular Genetics, 2014 Mutations in rhodopsin, the light-sensitive protein of rod cells, are the most common cause of autosomal dominant retinitis pigmentosa (ADRP). Many rod opsin mutations, such as P23H, lead to misfolding of rod opsin with detrimental effects on photoreceptor function and viability.
Dimitra Athanasiou +7 more
openalex +5 more sources
Evidence for multiple phototransduction pathways in a reef-building coral. [PDF]
PLoS ONE, 2012 Photosensitive behaviors and circadian rhythms are well documented in reef-building corals and their larvae, but the mechanisms responsible for photoreception have not been described in these organisms. Here we report the cloning, immunolocalization, and
Benjamin Mason +7 more
doaj +1 more source
Visual adaptation of opsin genes to the aquatic environment in sea snakes
BMC Evolutionary Biology, 2020 Background Evolutionary transitions from terrestrial to aquatic life history cause drastic changes in sensory systems. Indeed, the drastic changes in vision have been reported in many aquatic amniotes, convergently.
Takashi Seiko +8 more
doaj +1 more source
Evolution of the eyes of vipers with and without infrared-sensing pit organs [PDF]
, 2019 We examined lens and brille transmittance, photoreceptors, visual pigments, and visual opsin gene sequences of viperid snakes with and without infrared-sensing pit organs. Ocular media transmittance is high in both groups.
Douglas, R. H. +12 more
core +3 more sources
Multiple rod–cone and cone–rod photoreceptor transmutations in snakes: evidence from visual opsin gene expression [PDF]
Proceedings of the Royal Society B: Biological Sciences, 2016 In 1934, Gordon Walls forwarded his radical theory of retinal photoreceptor ‘transmutation’. This proposed that rods and cones used for scotopic and photopic vision, respectively, were not fixed but could evolve into each other via a series of morphologically distinguishable intermediates. Walls' prime evidence came from series of diurnal and nocturnal
Bruno F. Simões +8 more
openaire +3 more sources
Energy Transfer in Rhodopsin, N -Retinyl-Opsin, and Rod Outer Segments [PDF]
Proceedings of the National Academy of Sciences, 1971 N -retinyl, the chromophore of bleached and reduced rhodopsin, N -retinyl-opsin, was used as a covalently attached fluorescence probe to examine the structure of N -retinyl-opsin and the rod outer segment. The efficiency of energy transfer from the protein part of N
Thomas G. Ebrey
openalex +4 more sources
Loss of Motor Protein MYO1C Causes Rhodopsin Mislocalization and Results in Impaired Visual Function
Cells, 2021 Unconventional myosins, linked to deafness, are also proposed to play a role in retinal cell physiology. However, their direct role in photoreceptor function remains unclear.
Ashish K. Solanki +11 more
doaj +1 more source
An Ultrastructural and Immunohistochemical Analysis of the Outer Plexiform Layer of the Retina of the European Silver Eel (Anguilla anguilla L). [PDF]
PLoS ONE, 2016 Here we studied the ultrastructural organization of the outer retina of the European silver eel, a highly valued commercial fish species. The retina of the European eel has an organization very similar to most vertebrates.
Jan Klooster, Maarten Kamermans
doaj +1 more source
Tunicamycin blocks the incorporation of opsin into retinal rod outer segment membranes. [PDF]
Proceedings of the National Academy of Sciences, 1985 Isolated frog retinas were incubated with radiolabeled glycoprotein precursors in the presence or absence of tunicamycin (TM), a selective inhibitor of protein N-glycosylation. In dual-label incubations, TM inhibited the incorporation of [3H]mannose into total retina Cl3CCOOH-precipitable material by 85% relative to controls, whereas incorporation of ...
Steven J. Fliesler, Scott F. Basinger
openalex +4 more sources
Long-wavelength sensitive visual pigments of the guppy (): six opsins expressed in a single individual [PDF]
, 2007 Background The diversity of visual systems in fish has long been of interest for evolutionary biologists and neurophysiologists, and has recently begun to attract the attention of molecular evolutionary geneticists. Several recent studies
Weadick, Cameron J, Chang, Belinda S
core +2 more sources