Results 71 to 80 of about 6,500 (214)
Examining the role of the photopigment melanopsin in the striatal dopamine response to light
Frontiers in Systems NeuroscienceThe mesolimbic dopamine system is a set of subcortical brain circuits that plays a key role in reward processing, reinforcement, associative learning, and behavioral responses to salient environmental events.
L. Sofia Gonzalez +9 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2020 The photoreceptor outer segment is the canonical example of a modified and highly specialized cilium, with an expanded membrane surface area in the form of disks or lamellae for efficient light detection.
Stephen P. Carter +9 more
doaj +1 more source
Journal of Anatomy, Volume 248, Issue 5, Page 784-805, May 2026.The expression of various genes involved in synapse development, stability and/or function was studied in developing mechanosensory neuromasts and electrosensory ampullary organs in sterlet sturgeon. Most were shared, including Slc17a8, Slc1a3 and Nrxn3, but Cbln18 was neuromast‐restricted and Tulp1 was ampullary organ‐restricted.
Alexander S. Campbell +6 more
wiley +1 more source
Fractional integral-like processing in retinal cones reduces noise and improves adaptation. [PDF]
PLoS ONE, 2018 In the human retina, rod and cone cells detect incoming light with a molecule called rhodopsin. After rhodopsin molecules are activated (by photon impact), these molecules activate the rest of the signalling process for a brief period of time until they ...
Antal Martinecz, Mihoko Niitsuma
doaj +1 more source
A Novel Tree Shrew Model of Diabetic Retinopathy
Frontiers in Endocrinology, 2022 Existing animal models with rod-dominant retinas have shown that hyperglycemia injures neurons, but it is not yet clearly understood how blue cone photoreceptors and retinal ganglion cells (RGCs) deteriorate in patients because of compromised insulin ...
Oleg S. Gorbatyuk +8 more
doaj +1 more source
Molecular Aspects of Eye Evolution and Development: From the Origin of Retinal Cells to the Future of Regenerative Medicine [PDF]
, 2013 A central issue of evolutionary developmental biology is how the eye is diverged morphologically and functionally. However, the unifying mechanisms or schemes that govern eye diversification remain unsolved.
Ohuchi, Hideyo
core +1 more source
The FASEB Journal, Volume 40, Issue 7, 15 April 2026.We investigated the roles of PKM2, PKM1, and LDHA in retinal metabolism and structural integrity. In the normal retina, these enzymes are maintained at defined levels that support photoreceptor function. Rod‐specific deletion of LDHA, alone or with PKM2, caused age‐dependent degeneration, as PKM1 induction did not reach levels comparable to PKM2.
Ammaji Rajala +3 more
wiley +1 more source
Energy Transfer in Rhodopsin, N -Retinyl-Opsin, and Rod Outer Segments [PDF]
Proceedings of the National Academy of Sciences, 1971 N -retinyl, the chromophore of bleached and reduced rhodopsin, N -retinyl-opsin, was used as a covalently attached fluorescence probe to examine the structure of N -retinyl-opsin and the rod outer segment. The efficiency of energy transfer from the protein part of N
openaire +2 more sources
Rapid adaptive evolution of colour vision in the threespine stickleback radiation. [PDF]
, 2016 Vision is a sensory modality of fundamental importance for many animals, aiding in foraging, detection of predators and mate choice. Adaptation to local ambient light conditions is thought to be commonplace, and a match between spectral sensitivity and ...
Heckman, Nancy +4 more
core
Spatially differentiated expression of quadruplicated green-sensitive RH2 opsin genes in zebrafish is determined by proximal regulatory regions and gene order to the locus control region [PDF]
, 2015 BACKGROUND: Fish are remarkably diverse in repertoires of visual opsins by gene duplications. Differentiation of their spatiotemporal expression patterns and absorption spectra enables fine-tuning of feature detection in spectrally distinct regions of ...
Ryoko Masuda +3 more
core +1 more source