Localization of complement factor H gene expression and protein distribution in the mouse outer retina. [PDF]
, 2015 To determine the localization of complement factor H (Cfh) mRNA and its protein in the mouse outer retina.Quantitative real-time PCR (qPCR) was used to determine the expression of Cfh and Cfh-related (Cfhr) transcripts in the RPE/choroid.
Estep, Jason +6 more
core +1 more source
Occupancy of the Chromophore Binding Site of Opsin Activates Visual Transduction in Rod Photoreceptors [PDF]
The Journal of General Physiology, 1999 The retinal analogue β-ionone was used to investigate possible physiological effects of the noncovalent interaction between rod opsin and its chromophore 11-cis retinal. Isolated salamander rod photoreceptors were exposed to bright light that bleached a significant fraction of their pigment, were allowed to recover to a steady state, and then were ...
V J, Kefalov +2 more
openaire +2 more sources
EVOLUTION OF THE CIRCADIAN CLOCK IN EXTREME ENVIRONMENT: LESSONS FROM CAVEFISH. [PDF]
, 2010 Evolution has been strongly influenced by the daily cycles of temperature and light imposed by the rotation of the Earth. Fascinating demonstrations of this are seen in extreme environments such as caves where some animals have remained completely ...
Cavallari, Nicola
core
Human blue cone opsin regeneration involves secondary retinal binding with analog specificity [PDF]
, 2018 Human color vision is mediated by the red, green, and blue cone visual pigments. Cone opsins are G-protein-coupled receptors consisting of an opsin apoprotein covalently linked to the 11-cis-retinal chromophore.
Cordomi, Arnau +6 more
core +2 more sources
Case series: The value of fundus autofluorescence in inherited macular disease
Optometry and Vision Science, Volume 103, Issue 3, March 2026.ABSTRACT Purpose To evaluate the diagnostic utility of fundus autofluorescence (FAF) imaging in identifying and characterizing phenotypically classified inherited macular dystrophies. In this way, we aim to provide methods by which eye care practitioners can link FAF imaging and other clinical results or imaging modalities to aid their clinical ...
Marina Guro +6 more
wiley +1 more source
Ecology and Evolution, 2022 Among major vertebrate groups, anurans (frogs and toads) are understudied with regard to their visual systems, and little is known about variation among species that differ in ecology.
Ryan K. Schott +4 more
doaj +1 more source
Sensory Transduction and Subjective Experience: Expression of eight genes in three senses suggests a radical model of consciousness [PDF]
, 2007 Recent research into whole genome mapping of the mouse brain has made possible direct investigation of the brain expression of unusual genes. A search of the Allen Brain Atlas database has provided genetic and neuro-anatomical evidence for widespread ...
Chris C. King
core +1 more source
The mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein [PDF]
, 2011 Rapid regeneration of the visual pigment following its photoactivation is critical for the function of cone photoreceptors throughout the day. Though the reactions of the visual cycle in the retinal pigment epithelium (RPE) that recycle chromophore for ...
Crouch, Rosalie K +4 more
core +2 more sources
Visual Function Assessment in Geographic Atrophy: A Review
Clinical &Experimental Ophthalmology, Volume 54, Issue 2, Page 260-274, March 2026.ABSTRACT Geographic atrophy (GA) causes significant vision impairment and reduction in vision‐related quality of life. Fundus autofluorescence (FAF) is the gold standard of structural assessment of GA but is a surrogate marker for vision loss, which can be assessed by tests of visual function and functional vision.
Ye Li, Lauren N. Ayton, Adrian T. Fung
wiley +1 more source
P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis [PDF]
Human Molecular Genetics, 2013 Abstract Retinal rod photoreceptor cells have double membrane discs located in their outer segments (ROS) that are continuously formed proximally from connecting cilia (CC) and phagocytized distally by the retinal pigmented epithelium. The major component of these rod discs, the light-sensitive visual pigment rhodopsin (Rho), consists of
Sakami, Sanae +3 more
openaire +4 more sources