Results 81 to 90 of about 6,500 (214)
High‐Throughput In Vivo Subcellular Analysis of Gold Nanoparticles for Tumor Mitochondrial Targeting
Advanced Materials, Volume 38, Issue 16, 17 March 2026.A DNA barcoding system enables high‐throughput in vivo screening of mitochondrial‐targeting gold nanoparticles. Thirty nanoparticle types with varied shapes, sizes, and ligands are individually barcoded and pooled. The pooled library is administered to tumor‐bearing mice, and barcodes retrieved from tumor mitochondria are amplified and sequenced to ...
Xingyue Huang +8 more
wiley +1 more source
Tunicamycin blocks the incorporation of opsin into retinal rod outer segment membranes. [PDF]
Proceedings of the National Academy of Sciences, 1985 Isolated frog retinas were incubated with radiolabeled glycoprotein precursors in the presence or absence of tunicamycin (TM), a selective inhibitor of protein N-glycosylation. In dual-label incubations, TM inhibited the incorporation of [3H]mannose into total retina Cl3CCOOH-precipitable material by 85% relative to controls, whereas incorporation of ...
S J, Fliesler, S F, Basinger
openaire +2 more sources
Investigations into photoreceptor energy metabolism during experimental retinal detachment
Frontiers in Cellular Neuroscience, 2022 Retinal detachment is a sight-threatening disorder, which occurs when the photoreceptors are separated from their vascular supply. The aim of the present study was to shed light on photoreceptor energy metabolism during experimental detachment in rats ...
Glyn Chidlow +3 more
doaj +1 more source
Flavonoid allosteric modulation of mutated visual rhodopsin associated with retinitis pigmentosa [PDF]
, 2017 Dietary flavonoids exhibit many biologically-relevant functions and can potentially have beneficial effects in the treatment of pathological conditions. In spite of its well known antioxidant properties, scarce structural information is available on the ...
Garriga Solé, Pere +5 more
core +3 more sources
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
Advanced Science, Volume 13, Issue 14, 9 March 2026.This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
Biosynthesis and vectorial transport of opsin on vesicles in retinal rod photoreceptors. [PDF]
Journal of Histochemistry & Cytochemistry, 1986 Retinal rod photoreceptor cells absorb light at one end and establish synaptic contacts on the other. Light sensitivity is conferred by a set of membrane and cytosol proteins that are gathered at one end of the cell to form a specialized organelle, the rod outer segment (ROS).
D S, Papermaster +3 more
openaire +2 more sources
PLoS Computational Biology, 2020 For many species, vision is one of the most important sensory modalities for mediating essential tasks that include navigation, predation and foraging, predator avoidance, and numerous social behaviors.
Dharmeshkumar Patel +4 more
doaj +1 more source
Color vision diversity and significance in primates inferred from genetic and field studies [PDF]
, 2016 Color provides a reliable cue for object detection and identification during various behaviors such as foraging, mate choice, predator avoidance and navigation.
Shoji Kawamura
core +1 more source
Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes
Advanced Science, Volume 13, Issue 18, 27 March 2026.The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui +8 more
wiley +1 more source
Meckelin 3 is necessary for photoreceptor outer segment development in rat Meckel syndrome. [PDF]
PLoS ONE, 2013 Ciliopathies lead to multiorgan pathologies that include renal cysts, deafness, obesity and retinal degeneration. Retinal photoreceptors have connecting cilia joining the inner and outer segment that are responsible for transport of molecules to develop ...
Sarika Tiwari +5 more
doaj +1 more source