Results 121 to 130 of about 4,969,940 (302)

Role ambiguity and role conflict effects on employees’ emotional exhaustion in healthcare services in Tanzania

Cogent Business & Management
This study investigated the effect of role conflict and role ambiguity on emotional exhaustion among healthcare service employees in hospital settings. A questionnaire utilizing a 5-point Likert scale was administered to 181 employees of Kairuki Memorial
John R. P. Mwakyusa, Evelyne Willy Mcharo   +1 more
doaj   +1 more source

Religion, Psychiatric Symptoms, and Gender Role Conflict Among Incarcerated Black Men. [PDF]

Psychol Men Masc, 2023
Thorpe S, Stevens-Watkins D, Thrasher S, Malone N, Dogan JN.   +4 more
europepmc   +1 more source

A heuristic mathematical model for the dynamics of sensory conflict and motion sickness [PDF]

The etiology of motion sickness is now usually explained in terms of a qualitatively formulated sensory conflict hypothesis. By consideration of the information processing task faced by the central nervous system in estimating body spatial orientation ...
Oman, C. M.
core   +1 more source

The Manager’s Dilemma: Role Conflict in Marketing [PDF]

, 1978
Norris Brisco, Melvin Copeland, Henry Erdman, Benjamin Hibbard, George Hotchkiss, Leverett Lyon, Stanley Resor, Clarence Saunders, Harry Tosdal, Roland Vaile: Who are these people?
Armstrong, J. Scott
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

The influence of employees' perception of over-qualification on career compromise: Mediated by role conflict and sense of relative deprivation. [PDF]

Front Psychol, 2022
Zhou X, Zhang Y, Lin Y, Li L.
europepmc   +1 more source

The investment climate in post-conflict situations [PDF]

This paper is a policy review of the role of investment climate in post-conflict situations. It summarizes the broad range of ways in which conflict negatively affects the investment climate, from macroeconomic instability to a degraded regulatory ...
Mills, Rob, Qimiao Fan
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

How to Prevent Hostile Behaviors and Emotional Exhaustion among Law Enforcement Professionals: The Negative Spiral of Role Conflict. [PDF]

Int J Environ Res Public Health, 2023
López-Cabarcos MÁ, López-Carballeira A, Ferro-Soto C.   +2 more
europepmc   +1 more source