A heuristic mathematical model for the dynamics of sensory conflict and motion sickness [PDF]
The etiology of motion sickness is now usually explained in terms of a qualitatively formulated sensory conflict hypothesis. By consideration of the information processing task faced by the central nervous system in estimating body spatial orientation ...
Oman, C. M.
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Role conflict, job crafting, stress and resilience among nurses during COVID-19. [PDF]
Sahay S, Gigliotti RA, Dwyer M.
europepmc +1 more source
Mapping Perspectives on the EU as Mediator [PDF]
Research on the European Union’s role as a meditator is nascent. It predominantly focuses on case studies or is cursorily embedded within wider research on the European Union (EU) as a crisis manager. Moreover, there is a significant disconnect between
Haastrup, Toni
core
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Religion, Psychiatric Symptoms, and Gender Role Conflict Among Incarcerated Black Men. [PDF]
Thorpe S +4 more
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The influence of employees' perception of over-qualification on career compromise: Mediated by role conflict and sense of relative deprivation. [PDF]
Zhou X, Zhang Y, Lin Y, Li L.
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
On the Theory of Ethnic Conflict [PDF]
We present a theory of ethnic conflict in which coalitions formed along ethnic lines compete for the economy%u2019s resources. The role of ethnicity is to enforce coalition membership: in ethnically homogeneous societies members of the losing coalition ...
Francesco Caselli +1 more
core

