Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Conflict Resolution in the European Neighbourhood: The Role of the EU as a Framework and as an Actor [PDF]
The European Union's neighbourhood is rife with secessionist conflicts. The Union's proximity and its magnetic power of attraction has created the potential for a constructive European involvement in these regions. An EU role can be two-fold.
Nathalie Tocci
core
Personality and occupational correlates of anxiety and depression in nurses: the contribution of role conflict, core self-evaluations, negative affect and bullying. [PDF]
BMC Psychol, 2022 Hosseini Z, Homayuni A.
europepmc +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Entrepreneurial Activity and Civil War in Colombia: Exploring the Mutual Determinants between Armed Conflict and the Private Sector [PDF]
TAs elsewhere, the Colombian private sector has been accused of promoting or profiting from violence in the country. However, the private sector’s role in the armed conflict and the impact of conflict on entrepreneurial activity vary, as reflected by ...
Rettberg, Angelika +2 more
core
Workplace Bullying and Post-Traumatic Stress Disorder Symptomology: The Influence of Role Conflict and the Moderating Effects of Neuroticism and Managerial Competencies. [PDF]
Int J Environ Res Public Health, 2022 Chenevert M +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
, 2012 [[abstract]]This study was aimed at exploring not only the relations between work-family role values, role commitment, work hours input and work-family conflict, but also the mediating effect of work hours input during holidays between role commitment ...
Jiang, Yi-Ping
core
The Effect of Role Conflict and Professional Autonomy on the Role Performance of Patient Safety Coordinators in Small and Medium-Sized Hospitals in Korea. [PDF]
Int J Environ Res Public Health, 2022 Park KY, Kang K.
europepmc +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source