Results 151 to 160 of about 2,406,977 (306)

Work-Family Conflict and Facilitation among Employees in Hong Kong

open access: yes, 2014
Work-family imbalance can induce negative consequences, such as poor physical and psychological well-being for individuals. Hong Kong employees commonly agree that work-family balance is important for them, but it is difficult to balance work and family
Wong, Chi Kin
core  

The Role Of Emotions In Conflict And Conflict Resolution

open access: yes, 2019
Conflict has been a focal subject for research in social and political psychology along with politics, economics, sociology due to the changing world dynamics. In this literature review, while considering the increasing significance of the subject, constructive and destructive aspects of conflict are addressed and various definitions, dimensions and ...
openaire   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Life role salience and expectations about the work-family interface by Bailey Kropman.

open access: yes, 2012
Includes abstract.Includes bibliographical references.This study investigates the importance that young adults attribute to their future work and family roles and examines whether this helps predict significant variance in expectations about future work ...
Kropman, Bailey
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Are Job Demands Necessary in the Influence of a Transformational Leader? The Moderating Effect of Role Conflict. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Díaz-Fúnez PA   +3 more
europepmc   +1 more source

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