Results 121 to 130 of about 12,414,129 (288)
The investment climate in post-conflict situations [PDF]
This paper is a policy review of the role of investment climate in post-conflict situations. It summarizes the broad range of ways in which conflict negatively affects the investment climate, from macroeconomic instability to a degraded regulatory ...
Mills, Rob, Qimiao Fan
core
Environmental conflict and decision-making: the case of hydroelectric power
, 2012 As management of the environment becomes more complex and the number of potentially conflicting issues to be balanced expands, there will be increasing and more intense debates about the course(s) of action(s) to be taken.
Watkin, L, Watkin, L.
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Religion, Psychiatric Symptoms, and Gender Role Conflict Among Incarcerated Black Men. [PDF]
Psychol Men Masc, 2023 Thorpe S +4 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The Factors Associated with Burnout in Medical Support Staff Nurses
Nursing and Healthcare SciencePurpose: This study explored the factors associated with burnout in medical support staff nurses in tertiary hospitals. Method: A descriptive cross-sectional design was used.
So Young Heo, Heeok Park, Eun Kyung Kim
doaj +1 more source
The influence of employees' perception of over-qualification on career compromise: Mediated by role conflict and sense of relative deprivation. [PDF]
Front Psychol, 2022 Zhou X, Zhang Y, Lin Y, Li L.
europepmc +1 more source
A Scramble for Rents : Foreign Aid and Armed Conflict
, 2012 Previous research has not specified the circumstances under which foreign aid may increase the probability of armed conflict. The purpose of this dissertation is to address this gap by employing a theoretical framework in which foreign aid produces ...
Sollenberg, Margareta
core +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source