Results 71 to 80 of about 2,406,977 (306)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Gender role conflict and shame

open access: yes, 2018
Shame proneness has been shown to have serious implications on mental health. This study was designed to test a structural model of the relationship between traditional machismo, gender role conflict, and shame proneness, in Mexican men.
Brimhall, Andrew L.
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Conflict Prevention in Estonia: The Role of the Electoral System [PDF]

open access: yes, 2002
Estonia's success in averting a potential conflict over its Russian-speaking minority is often attributed to the intervention of the OSCE High Commissioner on National Minorities.
Khrychikov, Sergey   +2 more
core   +1 more source

The effect of role conflict on academic burnout of undergraduate Economics students

open access: yesInternational Journal of Research in Counseling and Education, 2020
Role conflict is experienced by students when incompatible demands relatively rated to a set of standards or conditions that influence their role performance. When students continuously experience role conflict, it leads to academic burnout.
Ayu Dina Kristina   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Konflik peran kerja-keluarga pada ibu bekerja terhadap perilaku obesogenis anak sekolah dasar

open access: yesJurnal Gizi Klinik Indonesia, 2014
Background: Childbearing pattern of parents greatly affects the healthy lifestyle of children including behaviors preventing children from obesity. Working mothers with a dual role at work and the family face challenges in doing so.
Almira Sitasari   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

States and Peoples in Conflict: Pillars, Forms, and Transformations in Conflict Studies

open access: yes, 2020
This introduction presents an overview of the key concepts covered in the subsequent chapters of this book. The book surveys theoretical and empirical research on the origins, processes, patterns, and consequences of most forms and contexts of political ...
Lichbach, Mark   +2 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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