Results 81 to 90 of about 2,406,977 (306)

The European Union, Conflict Transformation and Civil Society: A Conceptual Framework [PDF]

The European Union considers conflict resolution as a cardinal objective of its foreign policy. It makes use of a number of policy instruments to promote conflict transformation through ‘constructive engagement’, which cover a range of sectors affecting ...
Nathalie Tocci
core  

Role stress and work engagement as antecedents of job satisfaction in Spanish workers

Journal of Industrial Engineering and Management, 2014
Purpose: According to the Job Demands-Resources (JDR) model, engagement and job satisfaction may be produce by two types of working conditions: job demands (i.e. role stress) and job resources (i.e. self-efficacy).
Alejandro Orgambídez-Ramos, Yolanda Borrego-Alés, Isabel Mendoza-Sierra   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Conflict Management Styles in Croatian Enterprises – The Relationship between Individual Characteristics and Conflict Handling Styles [PDF]

The objective of the paper, except determining the dominant conflict handling style in Croatian organizational setting, was to explore individual characteristics affecting the choice of conflict resolution style of Croatian employees.
Nina Pološki Vokić, Sanja Sontor
core  

Identify the challenges of leadership in hospitals

Armaghane Danesh Bimonthly Journal, 2022
Background & aim: By accepting the responsibility of management and leadership, doctors are not completely separated from their medical duties. Usually, doctors have to follow their therapeutic duties while playing the role of leadership.
M Kabiri Naeini, H Jamali, Z Elahi
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Rehabilitating Health Systems in Post-Conflict Situations [PDF]

Although baseline data for post-conflict situations are frequently unavailable, there is a clear deterioration in the health conditions of populations during and following conflict. Excess mortality and morbidity, displaced populations, and vulnerability
Garrett, Brinnon, Waters, Hugh, Burnham, Gilbert   +2 more
core  

Preferences Under Pressure : Conflict, Threat Cues and Willingness to Compromise

, 2020
Understanding how preferences are formed is a key question in the social sciences. The ability of agents to interact with each other is a prerequisite for well-functioning societies. Nevertheless, the process whereby the preferences of agents in conflict
Skoog, Eric
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source