Results 81 to 90 of about 4,164 (194)
Osteonecrosis of the Jaw Associated with Antiangiogenics in Antiresorptive-Naive Patient: A Comprehensive Review of the Literature [PDF]
, 2018 Objectives. To review the available literature on medication-related osteonecrosis of the jaw (MRONJ) associated with antiangiogenics in antiresorptive-naïve individuals. Methods.
Fedele, S, Pimolbutr, K, Porter, S
core
Advanced Healthcare Materials, Volume 15, Issue 16, 24 April 2026.ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello +2 more
wiley +1 more source
The effect of romosozumab on bone mineral density depending on prior treatment: a prospective, multicentre cohort study in Switzerland. [PDF]
SUMMARY This multicentre, prospective cohort study measured the effect of romosozumab for 12 months on bone mineral density, taking into account prior therapies.
Everts-Graber, Judith +11 more
core +1 more source
Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis
Advanced Science, Volume 13, Issue 20, 9 April 2026.ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai +15 more
wiley +1 more source
Profile of romosozumab and its potential in the management of osteoporosis
Drug Design, Development and Therapy, 2017 Sian Yik Lim,1 Marcy B Bolster2 1Straub Bone & Joint Center, Straub Medical Center, Honolulu, HI, 2Division of Rheumatology, Allergy & Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA Abstract: Increased ...
Lim SY, Bolster MB
doaj
Scientific ReportsWe aimed to investigate the efficacy of romosozumab treatment compared with that of denosumab in especially male osteoporosis patients. This retrospective cohort study included 174 Japanese male patients receiving either denosumab or romosozumab for 12 ...
Tomonori Kobayakawa +3 more
doaj +1 more source
Romosozumab: from basic to clinical aspects [PDF]
Expert Opinion on Biological Therapy, 2014 The Wnt pathway has an important role in bone formation. Inactivation of sclerostin, an inhibitor of this pathway, has been associated with increased bone mass both in animal experiments and in human clinical trials. Romosozumab is a humanized monoclonal antibody targeting sclerostin.
openaire +3 more sources
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT This case report describes a newborn diagnosed with Type VII Osteogenesis Imperfecta (OI) following an incidental finding of rib fractures during evaluation for pneumonia. The patient presented with multiple fractures, including deformities and callus formations in the ribs and extremities, initially raising concerns for differential diagnoses
Samaneh Parviz, Dariush Hooshyar
wiley +1 more source
Une complication rare de la grossesse dans la région du sacrum [PDF]
, 2018 A
Anisau, Aliaksandr, Vanhoenacker, Filip
core +1 more source
Aging Cell, Volume 25, Issue 4, April 2026.Working model: MiR‐128‐3p inhibited the canonical Wnt signaling pathway by targeting Dvl2, resulting in reduced OB differentiation and age‐related osteoporosis. ABSTRACT MicroRNA‐128‐3p (miR‐128‐3p) has emerged as a crucial regulator of the aging process and age‐associated disorders. Recent research highlights the vital role of miR‐128‐3p in osteoclast
Gengyang Shen +13 more
wiley +1 more source