Results 91 to 100 of about 1,825,669 (338)
Baire reductions and good Borel reducibilities
, 2010 In reference [8] we have considered a wide class of "well-behaved" reducibilities for sets of reals. In this paper we continue with the study of Borel reducibilities by proving a dichotomy theorem for the degree-structures induced by good Borel ...
Ros, Luca Motto
core +1 more source
Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine [PDF]
, 2016 Reactive oxygen species (ROS) participate in numerous cell responses, including proliferation, DNA damage, and cell death. Based on these disparate activities, both promotion and inhibition of ROS have been proposed for cancer therapy.
Blyth, Karen +6 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
BMC PsychiatryBackground The implementation of peer-led programs provided by individuals with lived experience of mental disorders has been increasingly acknowledged as a key component in improving the quality of mental health services.
Maren Kjeldstad +4 more
doaj +1 more source
Antioxidants, 2020 Dietary habits are crucially important to prevent the development of lifestyle-associated diseases. Diets supplemented with chickpeas have numerous benefits and are known to improve body fat composition.
Mariangela Centrone +14 more
doaj +1 more source
Человек как мера. Беседа с Матсом Розенгреном о контексте возникновения доксологии [PDF]
, 2018 A subject of a conversation is the social context for the emergence of a doxology as a project of the naturalised theory of knowledge. The Swedish philosopher Mats Rosengren developed the doxology.
Nydahl, Mikael, Rosengren, Mats
core
Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells [PDF]
, 2010 Background - Surface charge and oxidative stress are often hypothesized to be important factors in cytotoxicity of nanoparticles. However, the role of these factors is not well understood.
Alink, G.M. +7 more
core +2 more sources
Key role for inhibins in effective T cell activation, migration and Th17 differentiation
FEBS Open Bio, EarlyView.Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco +5 more
wiley +1 more source
Redox Report, 2020 Objectives: Skeletal muscle adaptation to physical activity is dependent on various factors. Important signaling mediators are reactive oxygen species (ROS).
Angelika Schmitt +5 more
doaj +1 more source
Nanoparticles as Tools to Target Redox Homeostasis in Cancer Cells
Antioxidants, 2020 Reactive oxygen species (ROS) constitute a homeostatic rheostat that modulates signal transduction pathways controlling cell turnover. Most oncogenic pathways activated in cancer cells drive a sustained increase in ROS production, and cancer cells are ...
Francesco Ciccarese +4 more
doaj +1 more source