Results 11 to 20 of about 1,619,067 (258)

Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine [PDF]

open access: yes, 2016
Reactive oxygen species (ROS) participate in numerous cell responses, including proliferation, DNA damage, and cell death. Based on these disparate activities, both promotion and inhibition of ROS have been proposed for cancer therapy.
Blyth, Karen   +6 more
core   +1 more source

Protective effect of Artemisia absinthium on 6-hydroxydopamine-induced toxicity in SH-SY5Y cell line [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2021
Objective: Parkinson’s disease (PD) is a neurodegenerative disorder characterized by loss of dopaminergic neurons. Several experimental studies have shown neuroprotective and antioxidant effects for Artemisia absinthium. The present study was designed to
Roghayeh Rashidi   +3 more
doaj   +1 more source

Regulation of intracellular cyclic GMP concentration by light and calcium in electropermeabilized rod photoreceptors. [PDF]

open access: yes, 1994
This study examines the regulation of cGMP by illumination and by calcium during signal transduction in vertebrate retinal photoreceptor cells. We employed an electropermeabilized rod outer segment (EP-ROS) preparation which permits perfusion of low ...
Coccia, V J, Cote, Rick H.
core   +2 more sources

Inside the labyrinth : the thematics of space in the fiction of Paola Capriolo [PDF]

open access: yes, 2000
In Capriolo's fiction we see, above all, the centrality of place in the minds and lives of her protagonists, often linked with the idea of the labyrinth: labyrinth as endless tortuous passageways, enclosed place, puzzle, quest.
Ania, GF
core   +2 more sources

Quantitative analysis of NRF2 pathway reveals key elements of the regulatory circuits underlying antioxidant response and proliferation of ovarian cancer cells [PDF]

open access: yes, 2014
Cells are constantly exposed to Reactive Oxygen Species (ROS) produced both endogenously to meet physiological requirements and from exogenous sources.
Bown, James   +5 more
core   +4 more sources

La Lonja que no fue. Reflexiones e hipótesis sobre el proyecto inicial de la Lonja de Valencia.

open access: yesAnales de Historia del Arte, 2012
La historia de la arquitectura se ha hecho a partir de los edificios construidos o, en algunos casos, con proyectos utópicos o no ejecutados. Con ello, sin embargo, estaremos al final de un recorrido que, muchas veces, nos impide reconocer los modelos y ...
Federico Iborra Bernard   +1 more
doaj   +1 more source

Emodin Scavenging of Superoxide Radical Includes π–π Interaction. X-Ray Crystal Structure, Hydrodynamic Voltammetry and Theoretical Studies

open access: yesAntioxidants, 2020
The naturally occurring anthraquinone emodin is found in many plants that have been part of traditional Chinese medicine (TCM) for thousands of years.
Miriam Rossi   +3 more
doaj   +1 more source

Modulation of GCN2 activity under excess light stress by osmoprotectants and amino acids

open access: yesPlant Signaling & Behavior, 2022
The protein kinase GCN2 (General Control Nonderepressible2) and its phosphorylation target, the eukaryotic translation initiation factor (eIF)2α represent the core module of the plant’s integrated stress response, a signaling pathway widely conserved in ...
Ansul Lokdarshi   +2 more
doaj   +1 more source

Early redox activities modulate Xenopus tail regeneration. [PDF]

open access: yes, 2018
Redox state sustained by reactive oxygen species (ROS) is crucial for regeneration; however, the interplay between oxygen (O2), ROS and hypoxia-inducible factors (HIF) remains elusive.
Ferreira, Fernando   +4 more
core   +2 more sources

Autophagy Inhibition Induces the Secretion of Macrophage Migration Inhibitory Factor (MIF) with Autocrine and Paracrine Effects on the Promotion of Malignancy in Breast Cancer

open access: yesBiology, 2020
Breast cancer is the main cause of cancer-related death in women in the world. Because autophagy is a known survival pathway for cancer cells, its inhibition is currently being explored in clinical trials for treating several types of malignancies.
Israel Cotzomi-Ortega   +6 more
doaj   +1 more source

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