Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine [PDF]
Reactive oxygen species (ROS) participate in numerous cell responses, including proliferation, DNA damage, and cell death. Based on these disparate activities, both promotion and inhibition of ROS have been proposed for cancer therapy.
Blyth, Karen +6 more
core +1 more source
Protective effect of Artemisia absinthium on 6-hydroxydopamine-induced toxicity in SH-SY5Y cell line [PDF]
Objective: Parkinson’s disease (PD) is a neurodegenerative disorder characterized by loss of dopaminergic neurons. Several experimental studies have shown neuroprotective and antioxidant effects for Artemisia absinthium. The present study was designed to
Roghayeh Rashidi +3 more
doaj +1 more source
Regulation of intracellular cyclic GMP concentration by light and calcium in electropermeabilized rod photoreceptors. [PDF]
This study examines the regulation of cGMP by illumination and by calcium during signal transduction in vertebrate retinal photoreceptor cells. We employed an electropermeabilized rod outer segment (EP-ROS) preparation which permits perfusion of low ...
Coccia, V J, Cote, Rick H.
core +2 more sources
Inside the labyrinth : the thematics of space in the fiction of Paola Capriolo [PDF]
In Capriolo's fiction we see, above all, the centrality of place in the minds and lives of her protagonists, often linked with the idea of the labyrinth: labyrinth as endless tortuous passageways, enclosed place, puzzle, quest.
Ania, GF
core +2 more sources
Quantitative analysis of NRF2 pathway reveals key elements of the regulatory circuits underlying antioxidant response and proliferation of ovarian cancer cells [PDF]
Cells are constantly exposed to Reactive Oxygen Species (ROS) produced both endogenously to meet physiological requirements and from exogenous sources.
Bown, James +5 more
core +4 more sources
La Lonja que no fue. Reflexiones e hipótesis sobre el proyecto inicial de la Lonja de Valencia.
La historia de la arquitectura se ha hecho a partir de los edificios construidos o, en algunos casos, con proyectos utópicos o no ejecutados. Con ello, sin embargo, estaremos al final de un recorrido que, muchas veces, nos impide reconocer los modelos y ...
Federico Iborra Bernard +1 more
doaj +1 more source
The naturally occurring anthraquinone emodin is found in many plants that have been part of traditional Chinese medicine (TCM) for thousands of years.
Miriam Rossi +3 more
doaj +1 more source
Modulation of GCN2 activity under excess light stress by osmoprotectants and amino acids
The protein kinase GCN2 (General Control Nonderepressible2) and its phosphorylation target, the eukaryotic translation initiation factor (eIF)2α represent the core module of the plant’s integrated stress response, a signaling pathway widely conserved in ...
Ansul Lokdarshi +2 more
doaj +1 more source
Early redox activities modulate Xenopus tail regeneration. [PDF]
Redox state sustained by reactive oxygen species (ROS) is crucial for regeneration; however, the interplay between oxygen (O2), ROS and hypoxia-inducible factors (HIF) remains elusive.
Ferreira, Fernando +4 more
core +2 more sources
Breast cancer is the main cause of cancer-related death in women in the world. Because autophagy is a known survival pathway for cancer cells, its inhibition is currently being explored in clinical trials for treating several types of malignancies.
Israel Cotzomi-Ortega +6 more
doaj +1 more source

