Results 61 to 70 of about 1,619,067 (258)
BMC PsychiatryBackground The implementation of peer-led programs provided by individuals with lived experience of mental disorders has been increasingly acknowledged as a key component in improving the quality of mental health services.
Maren Kjeldstad +4 more
doaj +1 more source
Redox Report, 2020 Objectives: Skeletal muscle adaptation to physical activity is dependent on various factors. Important signaling mediators are reactive oxygen species (ROS).
Angelika Schmitt +5 more
doaj +1 more source
Nanoparticles as Tools to Target Redox Homeostasis in Cancer Cells
Antioxidants, 2020 Reactive oxygen species (ROS) constitute a homeostatic rheostat that modulates signal transduction pathways controlling cell turnover. Most oncogenic pathways activated in cancer cells drive a sustained increase in ROS production, and cancer cells are ...
Francesco Ciccarese +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Teaching the Basics of Reactive Oxygen Species and their Relevance to Cancer Biology: Mitochondrial Reactive Oxygen Species Detection, Redox Signaling, and Targeted Therapies [PDF]
, 2016 Reactive oxygen species (ROS) have been implicated in tumorigenesis (tumor initiation, tumor progression, and metastasis). Of the many cellular sources of ROS generation, the mitochondria and the NADPH oxidase family of enzymes are possibly the most ...
Bennett, Brian +5 more
core +1 more source
On the structure of finite level and \omega-decomposable Borel functions
, 2013 We give a full description of the structure under inclusion of all finite level Borel classes of functions, and provide an elementary proof of the well-known fact that not every Borel function can be written as a countable union of \Sigma^0_\alpha ...
Ros, Luca Motto
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
On the complexity of the relations of isomorphism and bi-embeddability
, 2011 Given an L_{\omega_1 \omega}-elementary class C, that is the collection of the countable models of some L_{\omega_1 \omega}-sentence, denote by \cong_C and \equiv_C the analytic equivalence relations of, respectively, isomorphism and bi-embeddability on ...
Ros, Luca Motto
core +1 more source
Biologia Plantarum, 2020 In plants, auxin/indoleacetic acid (Aux/IAA) proteins are transcriptional regulators, which regulate developmental process and responses to phytohormones and stress treatments.
G. LI +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source