Results 51 to 60 of about 746,641 (302)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

3D perception with ROS and PCL

open access: yes, 2014
18 FolienNowadays, first experiences in 3D perception can be easily obtained using ROS and PCL. ROS provides a communication layer and a user-friendly 3D visualization toolkit.
Arbeiter, Georg
core   +2 more sources

Fire Risk Model for Fires in Ro-Ro Ship Ro-Ro Spaces

open access: yesJournal of Risk Analysis and Crisis Response
In recent years, fire accidents on Ro-Ro ships have led to numerous fatalities and significant economic losses. The response of the crew and the ship's protection systems are crucial in managing these incidents and mitigating their consequences. To assess fire safety improvements, this study has focused on developing and quantifying a risk model that ...
Dahlbom, Sixten   +4 more
openaire   +3 more sources

Modification of the EEDI for Ro-ro Passenger Ships [PDF]

open access: yesSNAME Maritime Convention and 5th World Maritime Technology Conference, 2015
In the 3rd IMO GHG study the new data on the ships emissions indicate a clear need for improvements in ship energy efficiency in order to preserve the environment. Although the majority of the pollution originates from the international shipping, the environmental impact of the short-sea shipping, primarily from ro-ro passenger ships, should not be ...
Šestan, Ante   +2 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

AN ANALYSIS OF THE ITALIAN RO-RO AND RO-PAX NETWORK IN THE YEARS 2008-2015 [PDF]

open access: yesTransport Problems, 2018
In this paper, the development of Motorways of the Sea (MoS) services offered at Italian ports from 2008 to 2015 is analyzed. In particular, a detailed research on MoS routes calling at Italian ports in the year 2015 is carried out; within MoS routes: ro-pax and only cargo ro-ro services are identified.
Marino LUPI   +3 more
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Isolation of a Psychrotolerant and UV-C-Resistant Bacterium from Elephant Island, Antarctica with a Highly Thermoactive and Thermostable Catalase

open access: yesMicroorganisms, 2020
Microorganisms present in Antarctica have to deal not only with cold temperatures but also with other environmental conditions, such as high UV radiation, that trigger the generation of reactive oxygen species.
María T. Monsalves   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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