Results 51 to 60 of about 859,090 (292)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Modification of the EEDI for Ro-ro Passenger Ships [PDF]

SNAME Maritime Convention and 5th World Maritime Technology Conference, 2015
In the 3rd IMO GHG study the new data on the ships emissions indicate a clear need for improvements in ship energy efficiency in order to preserve the environment. Although the majority of the pollution originates from the international shipping, the environmental impact of the short-sea shipping, primarily from ro-ro passenger ships, should not be ...
Šestan, Ante, Ančić, Ivica, Vladimir, Nikola   +2 more
openaire   +2 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Ros bandt sound sculptor

, 2007
Ros Bandt is a composer-performer and sound artist, who is passionate about combining ancient and modern sonic practices. her sound research has included buildinga medieval Ptyhagorean recorder and she directs the Australian sound design project online ...
Mandelberg, John, Bandt, Ros, Sherman, Nikolai   +2 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

AN ANALYSIS OF THE ITALIAN RO-RO AND RO-PAX NETWORK IN THE YEARS 2008-2015 [PDF]

Transport Problems, 2018
In this paper, the development of Motorways of the Sea (MoS) services offered at Italian ports from 2008 to 2015 is analyzed. In particular, a detailed research on MoS routes calling at Italian ports in the year 2015 is carried out; within MoS routes: ro-pax and only cargo ro-ro services are identified.
Marino LUPI, Alessandro FARINA, Antonio PRATELLI, Letizia BELLUCCI   +3 more
openaire   +3 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Isolation of a Psychrotolerant and UV-C-Resistant Bacterium from Elephant Island, Antarctica with a Highly Thermoactive and Thermostable Catalase

Microorganisms, 2020
Microorganisms present in Antarctica have to deal not only with cold temperatures but also with other environmental conditions, such as high UV radiation, that trigger the generation of reactive oxygen species.
María T. Monsalves, Gabriela P. Ollivet-Besson, Maximiliano J. Amenabar, Jenny M. Blamey   +3 more
doaj   +1 more source

Fire Risk Model for Fires in Ro-Ro Ship Ro-Ro Spaces

Journal of Risk Analysis and Crisis Response
In recent years, fire accidents on Ro-Ro ships have led to numerous fatalities and significant economic losses. The response of the crew and the ship's protection systems are crucial in managing these incidents and mitigating their consequences. To assess fire safety improvements, this study has focused on developing and quantifying a risk model that ...
Dahlbom, Sixten, Andersson, Stina, De Carvalho, Eric, Lewandowski, Leon, Evegren, Franz   +4 more
openaire   +3 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source