Results 121 to 130 of about 12,098 (189)
Expression of C-terminal ALK, RET, or ROS1 in lung cancer cells with or without fusion
BMC Cancer, 2019 Background Genetic alterations, including mutation of epidermal growth factor receptor or v-Ki-ras2 kirsten rat sarcoma viral oncogene homolog and fusion of anaplastic lymphoma kinase (ALK), RET proto-oncogene (RET), or v-ros UR2 sarcoma virus oncogene ...
Koh Furugaki +5 more
doaj +1 more source
DNA methylation and epigenetic inheritance during plant gametogenesis [PDF]
, 2018 In plants, newly acquired epigenetic states of transcriptional gene activity are readily transmitted to the progeny. This is in contrast to mammals, where only rare cases of transgenerational inheritance of new epigenetic traits have been reported (FASEB
Paszkowski, Jerzy, Takeda, Shin
core
Role of Targeted Therapy and Immune Checkpoint Blockers in Advanced Non-Small Cell Lung Cancer: A Review. [PDF]
, 2019 Advanced non-small cell lung cancer (NSCLC) is a complex disease comprising molecularly distinct tumor types, each with a unique biology that is becoming increasingly better characterized.
Abdel Karim, Nagla, Kelly, Karen
core
Electron Bernstein waves emission in the TJ-II Stellarator
, 2011 Taking advantage of the electron Bernstein waves heating (EBWH) system of the TJ-II stellarator, an electron Bernstein emission (EBE) diagnostic was installed.
A Ros +22 more
core +1 more source
Expression and amplification of HER2 and molecular markers of signal activation in the advanced or metastatic lung carcinoma [PDF]
, 2018 Die Arbeit beleuchtet die Bedeutung des Signalmoleküls HER2 im Rahmen der intrazellulären Signalweiterleitung sowie seine Bedeutung als prognostischer bzw. prädiktiver Marker im fortgeschrittenen bzw.
Huber, Ulrich Cyril
core
Functional significance of U2AF1 S34F mutations in lung adenocarcinomas
Nature Communications, 2019 The authors report a co-occurrence of the U2AF1 S34F splicing factor mutation and ROS1 translocations in lung adenocarcinomas and profile effects of S34F on transcriptome-wide RNA binding. They further show that U2AF1 S34F enhances invasive potential and
Mohammad S. Esfahani +13 more
doaj +1 more source
Identification of chromosomal rearrangements in colorectal cancer [PDF]
, 2015 Curs 2014-2015Cancer research is continuously shedding light into these worldwide leading diseases. It is mandatory to have higher knowledge in cancer biology to consequently find out new candidate biomarkers and therapeutics.
Moratalla Navarro, Ferran
core
Pharmacological Research, 2017 ROS1 protein-tyrosine kinase fusion proteins are expressed in 1-2% of non-small cell lung cancers. The ROS1 fusion partners include CD74, CCDC6, EZR, FIG, KDELR2, LRIG3, MSN, SDC4, SLC34A2, TMEM106B, TMP3, and TPD52L1. Physiological ROS1 is closely related to the ALK, LTK, and insulin receptor protein-tyrosine kinases.
openaire +2 more sources
KLC1-ROS1 Fusion Exerts Oncogenic Properties of Glioma Cells via Specific Activation of JAK-STAT Pathway. [PDF]
Cancers (Basel), 2023 Fujii T +18 more
europepmc +1 more source