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Murine Roseolovirus Induces Autoimmune Gastritis and Disrupts Thymic Antigen Presenting Cells
Journal of Immunology, 2021Abstract Murine roseolovirus (MRV) is a beta-herpesvirus that is a natural murine pathogen and is genetically highly related to the human roseoloviruses, HHV6 and HHV7. The human roseoloviruses have been associated with autoimmune disease but demonstrating causality has been difficult due to the ubiquitous and chronic nature of ...
Mills Jason C, Yokoyama Wayne M
exaly +2 more sources
No Evidence for a Major Risk of Roseolovirus Vertical Transmission During Pregnancy
Clinical Infectious Diseases, 2003David Boutolleau +2 more
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Animal Models of Alzheimer’s Disease Should Be Controlled for Roseolovirus
Journal of Alzheimer's Disease, 2020Animal models to study Alzheimer’s disease (AD) pathogenesis are under development. Since herpesviruses have been postulated to be capable of triggering the pathogenic process, AD animal models (mouse, pig, and non-human primates) should be controlled for the presence of these viruses.
Joachim, Denner +2 more
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Porcine Cytomegalovirus/Porcine Roseolovirus (PCMV/PRV) and Antiviral Drugs
Xenotransplantationexaly +3 more sources
Xenotransplantation, 2023
AbstractBackgroundThe porcine cytomegalovirus, a porcine roseolovirus (PCMV/PRV), is widely distributed in pig populations. It has been shown that PCMV/PRV was transmitted by pig xenotransplants to non‐human primates, and significantly reduced the survival time of the recipient.
Joachim Denner +3 more
openaire +2 more sources
AbstractBackgroundThe porcine cytomegalovirus, a porcine roseolovirus (PCMV/PRV), is widely distributed in pig populations. It has been shown that PCMV/PRV was transmitted by pig xenotransplants to non‐human primates, and significantly reduced the survival time of the recipient.
Joachim Denner +3 more
openaire +2 more sources
Interactions of U24 from Roseolovirus with WW domains: canonical vs noncanonical
Biochemistry and Cell Biology, 2017U24 is a C-terminal membrane-anchored protein found in both human herpes virus type 6 and 7 (HHV-6 and HHV-7), with an N-terminal segment that is rich in prolines (PPxY motif in both HHV-6A and 7; PxxP motif in HHV-6A). Previous work has shown that U24 interacts strongly with Nedd4 WW domains, in particular, hNedd4L-WW3*.
Yurou, Sang +4 more
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