Results 71 to 80 of about 1,335 (123)

Additional file 1 of Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains

, 2022
Additional file 1: Supplementary Fig. 1. Peripheral, neonatal MRV infection in 5XFAD mice does not accelerate Aβ plaque burden. A, Schematic of experimental paradigm (6 mpi). B, C, Percent of CD4+ and CD8+ T cells in plasma 10 dpi (B) or 6 mpi (C). D, E, HJ3.4B+ immunostaining for Aβ plaque load in the cortex. F–I, Staining and quantification for Tau5+
Bigley, Tarin M., Xiong, Monica, Ali, Muhammad, Chen, Yun, Wang, Chao, Serrano, Javier Remolina, Eteleeb, Abdallah, Harari, Oscar, Yang, Liping, Patel, Swapneel J., Cruchaga, Carlos, Yokoyama, Wayne M., Holtzman, David M.   +12 more
openaire   +1 more source

High Torque teno virus load and outcome of patients undergoing allogeneic hematopoietic cell transplantation

Journal of Medical Virology, Volume 96, Issue 3, March 2024.
Abstract Quantification of Torque teno virus (TTV) load emerged as a marker of immunosuppression. Associations of TTV load with complications and survival after allogeneic hematopoietic cell transplantation (allo‐HCT) were controversial in published studies. In this prospective study, we aimed to identify factors influencing TTV load after allo‐HCT and
Micha Srour, Corentin Grenier, Leonardo Magro, Didier Hober, Ibrahim Yakoub‐Agha, Ilka Engelmann   +5 more
wiley   +1 more source

Additional file 3 of Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains

, 2022
Additional file 3: Supplementary Fig. 3. Effects of acute, intrahippocampal MRV infection on tau pathology. A, Schematic of experimental paradigm. B – G, Staining and quantification for Tau5+ total tau (B, C, D) and AT8+ phosphorylated tau in the cortex (E, F, G). p-tau: phosphorylated tau. Scale bar: 500 μm.
Bigley, Tarin M., Xiong, Monica, Ali, Muhammad, Chen, Yun, Wang, Chao, Serrano, Javier Remolina, Eteleeb, Abdallah, Harari, Oscar, Yang, Liping, Patel, Swapneel J., Cruchaga, Carlos, Yokoyama, Wayne M., Holtzman, David M.   +12 more
openaire   +1 more source

Emergence of novel circoviruses in humans and pigs and their possible importance for xenotransplantation and blood transfusions

Xenotransplantation, Volume 31, Issue 2, March/April 2024.
Abstract Background As sequencing is becoming more broadly available, virus discovery continues. Small DNA viruses contribute to up to 60% of the overall virus load in pigs. Porcine circoviruses (PCVs) are small DNA viruses with a single‐stranded circular genome.
Tanja Opriessnig, Chao‐Ting Xiao, Nicolas J. Mueller, Joachim Denner   +3 more
wiley   +1 more source

Additional file 2 of Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains

, 2022
Additional file 2: Supplementary Fig. 2. Comparisons between MRV purified and unpurified stocks. A – C, Stocks were created from in vivo passage and collection of 7 day post neonatal infection thymi and were used directly (MRV Stock) or semi-purified (MRV Purified).
Bigley, Tarin M., Xiong, Monica, Ali, Muhammad, Chen, Yun, Wang, Chao, Serrano, Javier Remolina, Eteleeb, Abdallah, Harari, Oscar, Yang, Liping, Patel, Swapneel J., Cruchaga, Carlos, Yokoyama, Wayne M., Holtzman, David M.   +12 more
openaire   +1 more source

Genetic diversity, growth and heart function of Auckland Island pigs, a potential source for organ xenotransplantation

Xenotransplantation, Volume 31, Issue 2, March/April 2024.
Abstract One of the prerequisites for successful organ xenotransplantation is a reasonable size match between the porcine organ and the recipient's organ to be replaced. Therefore, the selection of a suitable genetic background of source pigs is important.
Andreas Lange, Ivica Medugorac, Asghar Ali, Barbara Kessler, Mayuko Kurome, Valeri Zakhartchenko, Sabine E. Hammer, Andreas Hauser, Joachim Denner, Britta Dobenecker, Gerhard Wess, Paul L. J. Tan, Olga Garkavenko, Bruno Reichart, Eckhard Wolf, Elisabeth Kemter   +15 more
wiley   +1 more source

A broad wastewater screening and clinical data surveillance for virus-related diseases in the metropolitan Detroit area in Michigan

Human Genomics
Background Periodic bioinformatics-based screening of wastewater for assessing the diversity of potential human viral pathogens circulating in a given community may help to identify novel or potentially emerging infectious diseases.
Yabing Li, Brijen Miyani, Russell A. Faust, Randy E. David, Irene Xagoraraki   +4 more
doaj   +1 more source

Screening for Viruses in Indigenous Greek Black Pigs

Microorganisms
The successful advancement of xenotransplantation has led to the development of highly sensitive detection systems for the screening of potentially zoonotic viruses in donor pigs and preventing their transmission to the recipient.
Hina Jhelum, Vasileios Papatsiros, Georgios Papakonstantinou, Ludwig Krabben, Benedikt Kaufer, Joachim Denner   +5 more
doaj   +1 more source

Bioinformatics-based screening tool identifies a wide variety of human and zoonotic viruses in Trujillo-Peru wastewater

One Health
Peru was one of the most affected countries during the COVID-19 pandemic. Moreover, multiple other viral diseases (enteric, respiratory, bloodborne, and vector-borne) are endemic and rising.
Brijen Miyani, Yabing Li, Heidy Peidro Guzman, Ruben Kenny Briceno, Sabrina Vieyra, Rene Hinojosa, Irene Xagoraraki   +6 more
doaj   +1 more source

Detection of porcine cytomegalovirus, a roseolovirus, in pig ovaries and follicular fluid: Implications for somatic cells nuclear transfer, cloning and xenotransplantation [PDF]

, 2022
Sabrina Hansen, Konrad Fischer, Ludwig Krabben, Alexander Rinke Carrapeiro, Bernhard Klinger, Angelika Schnieke, Benedikt B. Kaufer, Joachim Denner   +7 more
openalex   +1 more source