Results 181 to 190 of about 90,351 (277)
ABSTRACT Enhancing both starch and protein accumulation is a key strategy for improving maize yield and quality. Achieving this goal requires an in‐depth understanding of the regulatory mechanisms that integrate these pathways. Here, we demonstrate that functionally redundant subclass III SNF1‐related protein kinase 2s (SnRK2s) act as central ...
Yayun Wang +16 more
wiley +1 more source
Targeted computational design of an interleukin-7 superkine with enhanced folding efficiency and immunotherapeutic efficacy. [PDF]
Lim SK +8 more
europepmc +1 more source
ABSTRACT Citrus Huanglongbing (HLB), a devastating disease caused by the unculturable bacterium ‘Candidatus Liberibacter asiaticus’ (CLas), poses a severe threat to global citrus production. CLas secretes effectors to suppress host immune responses and facilitate its colonisation. Previously, the CLas effector SECP8 (CLIBASIA_05330) has been identified
Mingyue Qin +8 more
wiley +1 more source
FakeRotLib: Expedient Noncanonical Amino Acid Parametrization in Rosetta. [PDF]
Bell EW, Brown BP, Meiler J.
europepmc +1 more source
ABSTRACT Abiotic stresses severely constrain soybean productivity worldwide. Here we demonstrate that gmeif2b5 (eukaryotic initiation factors) mutants confer dual stress tolerance through coordinated mechanisms. Integrative RNA‐Seq and protein interaction analyses revealed that gmeif2b5 mutants increase lignin deposition to increase drought resilience ...
Juan Liu +16 more
wiley +1 more source
Assessing Computational Strategies for the Evaluation of Antibody Binding Affinities. [PDF]
Autiero I +7 more
europepmc +1 more source
ABSTRACT Autophagy and the ubiquitin/26S proteasome system (UPS) play critical roles in the immune defence of the host against pathogen invasion. As a countermeasure, pathogens deploy effector proteins to subvert or hijack autophagy and UPS processes.
Yaqian Shi +7 more
wiley +1 more source
Docking With Rosetta and Deep Learning Approaches in CAPRI Rounds 47-55. [PDF]
Harmalkar A +8 more
europepmc +1 more source
A DNA‐Based Binding Assay for the m6A‐RNA Reader Proteins
We report the structure of the m6A‐RNA reader YTHDC2 in the complex with single‐stranded DNA. We provide evidence that the readers exhibit slightly stronger affinity for 6mA‐modified DNA than RNA. Thus, we developed an FP binding assay that uses single‐stranded DNA as probe.
Rajiv Kumar Bedi, Amedeo Caflisch
wiley +1 more source
The Clausius-Mossotti Factor in Dielectrophoresis: A Critical Appraisal of Its Proposed Role as an 'Electrophysiology Rosetta Stone'. [PDF]
Pethig R.
europepmc +1 more source

