Plasmodium falciparum rosetting epitopes converge in the SD3-loop of PfEMP1-DBL1α. [PDF]
PLoS ONE, 2012 The ability of Plasmodium falciparum parasitized RBC (pRBC) to form rosettes with normal RBC is linked to the virulence of the parasite and RBC polymorphisms that weaken rosetting confer protection against severe malaria.
Davide Angeletti +10 more
doaj +5 more sources
Improved in vitro culture of Plasmodium falciparum permits establishment of clinical isolates with preserved multiplication, invasion and rosetting phenotypes. [PDF]
PLoS ONE, 2013 To be able to robustly propagate P. falciparum at optimal conditions in vitro is of fundamental importance for genotypic and phenotypic studies of both established and fresh clinical isolates. Cryo-preserved P.
Ulf Ribacke +10 more
doaj +2 more sources
Phenotypic and genotypic characterization of Plasmodium falciparum field isolates lacking pfhrp2 gene [PDF]
Malaria JournalBackground The Plasmodium falciparum phenotypic characteristics (cytoadherence and rosetting), and the concentration of Histidine Rich Protein 2 (HRP2) in serum are associated with severe malaria in regions like Africa and Asia.
Jorge Bendezu +5 more
doaj +2 more sources
Rifins, rosetting, and red blood cells
Trends in Parasitology, 2015 The binding of multiple uninfected erythrocytes to a central malaria parasite-infected erythrocyte (IE) is called rosetting. Rosetting has been associated with severe disease, but its functional significance,and the host receptors and parasite ligands involved are only partially known.
Wang, Christian W, Hviid, Lars
openaire +4 more sources
The effect of anti-rosetting agents against malaria parasites under physiological flow conditions. [PDF]
PLoS ONE, 2013 Rosetting remains the dominant malaria parasite adhesion phenotype associated with severe disease and pathogenicity in Africa. The formation of rosettes, whereby a Plasmodium falciparum infected erythrocyte (IE) adheres to two or more non-IEs, is thought
Yvonne Adams, J Alexandra Rowe
doaj +2 more sources
Structural basis for the ABO blood-group dependence of Plasmodium falciparum rosetting.
PLoS Pathogens, 2012 The ABO blood group influences susceptibility to severe Plasmodium falciparum malaria. Recent evidence indicates that the protective effect of group O operates by virtue of reduced rosetting of infected red blood cells (iRBCs) with uninfected RBCs ...
Inès Vigan-Womas +11 more
doaj +2 more sources
Plasmodium chabaudi: rosetting in a rodent malaria model
Experimental Parasitology, 2002 Rosetting is a property of many malaria parasite species that has been linked to virulence in the major species infecting humans, Plasmodium falciparum. Here, the basic properties of rosettes in the rodent malaria laboratory model, P. chabaudi, were studied with a view to future studies on the role of rosetting in malaria parasite virulence and ...
Mackinnon, M, Walker, P, Rowe, J
openaire +4 more sources
Association of platelet satellitism with immune thrombocytopenia: A case report and review of literature [PDF]
eJHaemPlatelet satellitism refers to the rosetting of the platelets around white blood cells, mostly neutrophils that could lead to spuriously low platelet counts on automated analyzers. The phenomenon has usually been described in EDTA processed blood samples.
Junaid A. Wali +2 more
doaj +2 more sources
eLife, 2020 In malaria, rosetting is described as a phenomenon where an infected erythrocyte (IRBC) is attached to uninfected erythrocytes (URBC). In some studies, rosetting has been associated with malaria pathogenesis.
Wenn-Chyau Lee +14 more
doaj +1 more source
Rosettes integrity protects Plasmodium vivax of being phagocytized
Scientific Reports, 2020 Plasmodium vivax is the most prevalent cause of malaria outside of Africa. P. vivax biology and pathogenesis are still poorly understood. The role of one highly occurring phenotype in particular where infected reticulocytes cytoadhere to noninfected ...
Letusa Albrecht +16 more
doaj +1 more source