Results 31 to 40 of about 4,807 (280)

Red blood cell blood group A antigen level affects the ability of heparin and PfEMP1 antibodies to disrupt Plasmodium falciparum rosettes

Malaria Journal, 2021
Background The histo-blood group ABO system has been associated with adverse outcomes in COVID-19, thromboembolic diseases and Plasmodium falciparum malaria.
Pontus Hedberg, Madle Sirel, Kirsten Moll, Mpungu Steven Kiwuwa, Petter Höglund, Ulf Ribacke, Mats Wahlgren   +6 more
doaj   +1 more source

Evolving perspectives on rosetting in malaria

Trends in Parasitology, 2022
The ability of the intraerythrocytic Plasmodium spp. to form spontaneous rosettes with uninfected red blood cells (URBCs) has been observed in the medically important malaria parasites. Since the discovery of rosettes in the late 1980s, different formation mechanisms and pathobiological roles have been postulated for rosetting; most of which have ...
Wenn-Chyau Lee, Bruce Russell, Laurent Rénia   +2 more
openaire   +3 more sources

Glycophorin C (CD236R) mediates vivax malaria parasite rosetting to normocytes

, 2020
Rosetting phenomenon has been linked to malaria pathogenesis. Although rosetting occurs in all causes of human malaria, most data on this subject has been derived from Plasmodium falciparum. Here, we investigate the function and factors affecting rosette
Albrecht, L., Lee, W. C., Cho, J. S., Mauduit, M., Preiser, P., Nosten, F., Zhang, R., Malleret, B., Renia, L., McGready, R., Lau, Y. L., Russell, B., Suwanarusk, R., Costa, F. T. M., Fong, M. Y.   +14 more
core   +2 more sources

Immunogenicity of the Plasmodium falciparum PfEMP1-VarO Adhesin: Induction of Surface-Reactive and Rosette-Disrupting Antibodies to VarO Infected Erythrocytes. [PDF]

PLoS ONE, 2015
Adhesion of Plasmodium falciparum-infected red blood cells (iRBC) to human erythrocytes (i.e. rosetting) is associated with severe malaria. Rosetting results from interactions between a subset of variant PfEMP1 (Plasmodium falciparum erythrocyte membrane
Micheline Guillotte, Alexandre Juillerat, Sébastien Igonet, Audrey Hessel, Stéphane Petres, Elodie Crublet, Cécile Le Scanf, Anita Lewit-Bentley, Graham A Bentley, Inès Vigan-Womas, Odile Mercereau-Puijalon   +10 more
doaj   +1 more source

Immunisation with recombinant PfEMP1 domains elicits functional rosette-inhibiting and phagocytosis-inducing antibodies to Plasmodium falciparum.

PLoS ONE, 2011
BackgroundRosetting is a Plasmodium falciparum virulence factor implicated in the pathogenesis of life-threatening malaria. Rosetting occurs when parasite-derived P.
Ashfaq Ghumra, Pongsak Khunrae, Ricardo Ataide, Ahmed Raza, Stephen J Rogerson, Matthew K Higgins, J Alexandra Rowe   +6 more
doaj   +1 more source

Microscopy-based Methods for Rosetting Assay in Malaria Research

Bio-Protocol, 2020
In malaria, rosetting phenomenon is a condition where a Plasmodium-infected erythrocyte stably adheres to at least an uninfected erythrocyte. This phenomenon that occurs in all species of human malaria parasite is likely to be an immune escape mechanism ...
Wenn-Chyau Lee, Laurent Rénia
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Detection of naturally acquired, strain-transcending antibodies against rosetting <i>Plasmodium falciparum</i> strains in humans. [PDF]

Infect Immun
Strain-transcending antibodies against virulence-associated subsets of P. falciparum-infected erythrocyte surface antigens could protect children from severe malaria.
McLean FE, Azasi Y, Sutherland C, Toboh E, Ansong D, Agbenyega T, Awandare G, Rowe JA.   +7 more
europepmc   +2 more sources

Plasmodium falciparum Rosette Formation Assay

Bio-Protocol, 2013
Rosetting, i.e. the capacity of red blood cells (iRBCs) infected with mature parasite stages to bind two or more uninfected red blood cells (RBCs) is a virulence factor of Plasmodium falciparum.
Inès Vigan-Womas, Micheline Guillotte, Odile Mercereau-Puijalon   +2 more
doaj   +1 more source

Insights into the Cytoadherence Phenomenon of Plasmodium vivax: The Putative Role of Phosphatidylserine

Frontiers in Immunology, 2017
Plasmodium vivax is the most geographically widespread and the dominant human malaria parasite in most countries outside of sub-Saharan Africa and, although it was classically recognized to cause benign infection, severe cases and deaths caused by P ...
Paulo Renato Totino, Stefanie Costa Lopes   +1 more
doaj   +1 more source