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Evolution of rosmarinic acid biosynthesis
Phytochemistry, 2009Rosmarinic acid and chlorogenic acid are caffeic acid esters widely found in the plant kingdom and presumably accumulated as defense compounds. In a survey, more than 240 plant species have been screened for the presence of rosmarinic and chlorogenic acids. Several rosmarinic acid-containing species have been detected.
Maike Petersen
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The antibacterial mechanism of perilla rosmarinic acid
Biotechnology and Applied Biochemistry, 2021AbstractRosmarinic acid (RosA) is a phenolic acid compound extracted from perilla. In this experiment, the Oxford cup method was used to verify the antibacterial activity of PerillaRosA against Escherichia coli, Staphylococcus aureus, Salmonella, and Bacillus subtilis.
Jinhua Zhang +5 more
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Therapeutic Potential of Rosmarinic Acid: A Comprehensive Review [PDF]
Applied Sciences (Switzerland), 2019 Naturally occurring food-derived active ingredients have received huge attention for their chemopreventive and chemotherapy capabilities in several diseases. Rosmarinic acid (RA) is a caffeic acid ester and a naturally-occurring phenolic compound in a number of plants belonging to the Lamiaceae family, such as Rosmarinus officinalis (rosemary) from ...
Ghulam Hussain +2 more
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Neurobehavioral and genotoxic aspects of rosmarinic acid
Pharmacological Research, 2005Rosmarinic acid is a naturally occurring hydroxylated compound. It is present in many plants, for example, it occurs in Artemisia capillaris, Calendulla officinalis, Melissa officinalis, Salvia officinalis and in other several plant families. It also shows a number of interesting biological activities, e.g.
Patricia Pereira, Jaqueline Picada
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Metabolism of Rosmarinic Acid in Rats
Journal of Natural Products, 1998The urine of rats administered rosmarinic acid (7) orally contained seven metabolites, which were identified as trans-caffeic acid 4-O-sulfate (1), trans-m-coumaric acid 3-O-sulfate (2), trans-ferulic acid 4-O-sulfate (3), trans-caffeic acid (4), m-hydroxyphenylpropionic acid (5), trans-m-coumaric acid (6), and unchanged rosmarinic acid (7) by ...
T, Nakazawa, K, Ohsawa
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Effect of rosmarinic acid on atopic dermatitis
The Journal of Dermatology, 2008ABSTRACTRosmarinic acid is known to have anti‐inflammatory and immunomodulatory activities. This study was performed to evaluate the effect of rosmarinic acid on atopic dermatitis (AD), one of the inflammatory disorders of the skin. Twenty‐one subjects (14 women and seven men, 5–28 years of age) with mild AD participated in this study. Rosmarinic acid (
Jongsung, Lee +4 more
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Caffeic acid and rosmarinic acid contents in genus Perilla
Journal of Natural Medicines, 2020Caffeic acid and rosmarinic acid are common components of Labiatae plants, such as shiso (Perilla frutescens Britton var. crispa W. Deane) and Boraginaceae plants. These compounds have various pharmacological activities, such as anti-inflammatory, anti-anxiety, and anti-depressive activities, but the content of these compounds in perilla has not been ...
Yuya Deguchi, Michiho Ito
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Redox Behaviour of Verbascoside and Rosmarinic Acid
Combinatorial Chemistry & High Throughput Screening, 2013The electrochemical oxidation mechanisms of rosmarinic acid (RA) and verbascoside (VB), both caffeic acid esters with two catechol moieties, were investigated. The redox mechanism is associated with the oxidation of the catechol groups, and was studied over a wide pH range by cyclic, differential pulse and square wave voltammetry, using a glassy carbon
Eric de Souza, Gil +2 more
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The effect of rosmarinic acid on the prevention of myringosclerosis
International Journal of Pediatric Otorhinolaryngology, 2019Myringosclerosis commonly occurs as a long-term complication of ventilation during the treatment of otitis media. We aimed to determine the effects of rosmarinic acid as an antioxidant on experimentally induced myringosclerosis.Twenty-four male Sprague-Dawley rats, weighing 250-300 g, were unilaterally myringotomized and randomly separated into three ...
Doğukan Özdemir +6 more
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Attenuation of Tacrine Combined With Rosmarinic Acid
Phytochemical AnalysisABSTRACTBackgroundAlzheimer's disease (AD) is one of the most common forms of dementia among the elderly in the world. With the increase of human life expectancy, its incidence is also increasing year by year. Tacrine (TAC) is the first acetylcholine inhibitor approved for the treatment of AD.
Manyv Zheng +6 more
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