Results 31 to 40 of about 31,394 (214)
Pharmaceutical Research, 2021 To build a physiologically based pharmacokinetic (PBPK) model of the clinical OATP1B1/OATP1B3/BCRP victim drug rosuvastatin for the investigation and prediction of its transporter-mediated drug-drug interactions (DDIs).
N. Hanke +4 more
semanticscholar +1 more source
EFFECTS OF ROSUVASTATIN IN EXPERIMENTALLY-INDUCED CARDIAC ISCHEMIA AND ON AORTIC VASCULAR REACTIVITY. [PDF]
Al-Azhar Journal of Pharmaceutical Sciences, 2017 Myocardial infarction (MI) continues to be a major public health problem in the world. The present study aimed to elucidate the protective effect of different doses of rosuvastatin and cilostazol, as well as their combination on isoprenaline-induced MI
Maryam Hamouda
doaj +1 more source
BMC Medicine, 2020 Background Inflammation contributes to the pathophysiology of major depressive disorder (MDD), and anti-inflammatory strategies might therefore have therapeutic potential. This trial aimed to determine whether adjunctive aspirin or rosuvastatin, compared
M. Berk +30 more
semanticscholar +1 more source
Clinical Pharmacokinetics, 2021 The first oral glucagon-like peptide-1 receptor agonist (GLP-1RA) comprises semaglutide co-formulated with the absorption enhancer, sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC). Oral semaglutide may alter the pharmacokinetics of co-administered
Andreas B. Jordy +7 more
semanticscholar +1 more source
Clinical and Translational Science, 2019 This study evaluated the utility of combination of digoxin (0.25 mg) and rosuvastatin (5 mg) as a new transporter (P‐glycoprotein/breast cancer resistance protein/organic anion‐transporting polypeptide (OATP)1B1/OATP1B3) probe cocktail (Oita combination)
Naoyuki Otani +11 more
doaj +1 more source
Cardiovascular Diabetology, 2005 Objective The Use of Rosuvastatin versus Atorvastatin iN type 2 diabetes mellitUS (URANUS) study compared rosuvastatin with atorvastatin for the reduction of low-density lipoprotein cholesterol (LDL-C) in patients with type 2 diabetes.
Berne Christian, Siewert-Delle Annica
doaj +1 more source
Rosuvastatin is Superior Compared to Simvastatin and Atorvastatin to Induce Endothelial Progenitor Cells Migration [PDF]
Journal of Clinical and Diagnostic Research, 2019 Introduction: Statins have shown to improve Endothelial Progenitor Cells (EPCs) function, however no comparison has been done between various statins effectivity to induce EPCs migration.
Yudi Her Oktaviono +4 more
doaj +1 more source
EBioMedicine, 2016 Statins are beneficial in the treatment of cardiovascular disease (CVD), but these lipid-lowering drugs are associated with increased incidence of new on-set diabetes.
Vishal A. Salunkhe +9 more
doaj +1 more source
The impact of rosuvastatin on inflammatory markers in L-NAME induced hypertensive rats
Zanco Journal of Medical Sciences, 2023 Background and objective: Many clinical trials have revealed that HMG-CoA reductase inhibitors (statins) have anti-inflammatory effects through their pleiotropic activities there by decreasing the risk of cardiovascular disease (CVD). This study intended
Kawa F. Dizaye, Begard O. Berzinji
doaj +1 more source
Clinical Therapeutics, 2021 PURPOSE We investigated whether the combination therapy of low-intensity rosuvastatin and ezetimibe is an useful alternative to moderate-intensity rosuvastatin monotherapy in patients requiring cholesterol-lowering therapy.
Seung-Ah Lee +15 more
semanticscholar +1 more source