Results 51 to 60 of about 20,176 (178)

Pharmacokinetic and pharmacodynamic interaction between ezetimibe and rosuvastatin in healthy male subjects

open access: yesDrug Design, Development and Therapy, 2017
Chang Hee Kim,1 Hyungmi An,2 Sung Hye Kim,3 Dongseong Shin4 1Department of Urology, Gachon University Gil Medical Center, Incheon, 2Department of Statistics, Seoul National University, Seoul, 3Clinical Development, Navipharm Co., Ltd., Suwon ...
Kim CH, An H, Kim SH, Shin D
doaj  

Rosuvastatin 20 mg restores normal HDL-apoA-I kinetics in type 2 diabetes

open access: yesJournal of Lipid Research, 2009
Catabolism of HDL particles is accelerated in type 2 diabetes, leading to a reduction in plasma residence time, which may be detrimental. Rosuvastatin is the most powerful statin to reduce LDL-cholesterol, but its effects on HDL metabolism in type 2 ...
Bruno Vergès   +8 more
doaj   +1 more source

Rosuvastatin-Induced Thrombocytopenia

open access: yesSouthern Medical Journal, 2010
Rosuvastatin, a statin indicated for patients with primary hypercholesterolemia, mixed dyslipidemia and familial hypercholesterolemia, is well tolerated by most patients. Its most common adverse effects are gastrointestinal derangement, muscle aches and hepatitis. One rare complication of statin treatment is severe thrombocytopenia.
Vrettos, I.   +7 more
openaire   +3 more sources

Genomic and Sex Contributions to Interindividual Variability in Pitavastatin Bioavailability

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Aim This study investigates pharmacogenetic determinants of pitavastatin disposition using a candidate‐gene approach. Methods In 48 healthy volunteers, 138 variants across 40 genes involved in drug metabolism and transport were analysed to assess their relationship with pitavastatin pharmacokinetics, alongside the influence of sex and ...
Eva González‐Iglesias   +7 more
wiley   +1 more source

Optimization of UPLC method for simultaneous determination of rosuvastatin and rosuvastatin degradation products

open access: yesActa Chimica Slovenica, 2017
An ultra-performance liquid chromatographic method for simultaneous determination of rosuvastatin and rosuvastatin degradation products was developed and optimized by using fractional factorial experimental design.
Jure Zakrajšek   +3 more
doaj   +2 more sources

Impact of treatment with rosuvastatin and atorvastatin on cardiovascular outcomes: evidence from the Archimedes-simulated clinical trials

open access: yesClinicoEconomics and Outcomes Research, 2015
Furio Colivicchi,1 Catarina Sternhufvud,2 Sanjay K Gandhi3 1Cardiology Division, Emergency Department, San Filippo Neri Hospital, ASL Roma E, Rome, Italy; 2Global Payer Evidence and Pricing, AstraZeneca R&D, Mölndal, Sweden; 3Global Health ...
Colivicchi F, Sternhufvud C, Gandhi SK
doaj  

Clinical, Radiographic, and Histopathologic Features of Human Perigraftitis

open access: yesJournal of Esthetic and Restorative Dentistry, Volume 38, Issue 7, Page 1300-1314, July 2026.
ABSTRACT Objective Perigraftitis is a biologic complication associated with dental implants placed in grafted bone, distinct from peri‐implant mucositis and peri‐implantitis. This report further characterizes its clinical, radiographic, and histopathologic features.
Jonathan H. Do   +2 more
wiley   +1 more source

A pharmacokinetic and pharmacodynamic drug interaction between rosuvastatin and valsartan in healthy subjects

open access: yesDrug Design, Development and Therapy, 2015
Jin Ah Jung,1 Soo-Yun Lee,2 Jung-Ryul Kim,1 Jae-Wook Ko,1,2 Seong Bok Jang,3 Su Youn Nam,3 Wooseong Huh1,41Department of Clinical Pharmacology and Therapeutics, Samsung Medical Center, 2Department of Health Sciences and Technology, Samsung Advanced ...
Jung JA   +6 more
doaj  

Physically active adults with uncomplicated type 1 diabetes exhibit normal cardiopulmonary exercise test responses versus healthy controls

open access: yesPhysiological Reports, Volume 14, Issue 13, July 2026.
Physically active adults with uncomplicated type 1 diabetes and healthy controls completed incremental cycling cardiopulmonary exercise testing with measurements at rest, ventilatory thresholds 1 and 2, and peak exercise. Linear mixed‐effects models showed no statistically detectable Group effects or Group × Stage interactions for conventional ...
Samu Sorola   +7 more
wiley   +1 more source

Managing hypercholesterolemia and preventing cardiovascular events in elderly and younger Chinese adults: focus on rosuvastatin

open access: yesClinical Interventions in Aging, 2013
Zhen Wang, Junbo GeDepartment of Cardiology, Zhongshan Hospital, Shanghai, People's Republic of ChinaAbstract: Coronary heart disease (CHD) is the leading cause of death worldwide.
Wang Z, Ge JB
doaj  

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