Results 61 to 70 of about 20,176 (178)
The farnesoid X receptor -1G>T polymorphism influences the lipid response to rosuvastatin
Journal of Lipid Research, 2012 The bile acid-activated nuclear receptor farnesoid X receptor (FXR) plays an important role in lipid and glucose metabolism, and in addition, it regulates multiple drug transporters involved in statin disposition.
Miao Hu +4 more
doaj +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1934-1939, June 2026.Pharmacogenomic (PGx) information has the potential to support the safe and effective use of medicines, yet there is uncertainty about how this information can be best communicated to patients. Summaries of product characteristics (SmPCs) and patient information leaflets (PILs) for all UK‐approved medicines with strong evidence supporting a PGx ...
Parth Narlawar +5 more
wiley +1 more source
Gastroenterology Research and Practice, 2010 Background and Aims. An arterial blood supply and phenotypic changes of the sinusoids characterise the liver vasculature in human hepatocellular carcinoma (HCC).
Annemilaï Tijeras-Raballand +8 more
doaj +1 more source
APOE and Cerebral Microbleeds: Insights Into Causal Proteins and Therapeutic Targets
Brain and Behavior, Volume 16, Issue 6, June 2026.This study identifies APOE as a key causal protein for cerebral microbleeds (CMBs). By integrating Mendelian randomization (MR) and colocalization analysis of the plasma proteome from UKB‐PPP and deCODE datasets, we provide genetic evidence that circulating APOE levels are causally linked to CMB susceptibility. Furthermore, protein–protein interaction (
Lei Yang +8 more
wiley +1 more source
Planning and evaluation of bioequivalence studies of rosuvastatin drug products
Регуляторные исследования и экспертиза лекарственных средств, 2018 The article reviews bioequivalence studies of Russian and foreign generic rosuvastatin preparations with the goal of harmonizing approaches to rosuvastatin bioequivalence studies in the Russian Federation.
D. P. Romodanovsky, D. V. Goryachev
doaj
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Jejunal diverticulosis is a rare cause of obscure gastrointestinal bleeding (OGIB) that can present with life‐threatening hemorrhage. We report a 69‐year‐old male with recurrent melena, severe anemia, and hemodynamic instability requiring multiple transfusions. Upper and lower endoscopy were nondiagnostic, and CT angiography failed to localize
Mahmoud Draidi +5 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Persistent diarrhea during anticancer therapy may not be attributable to anticancer agents. Our patient presented with diarrhea during lenvatinib–pembrolizumab therapy, likely caused by lansoprazole‐induced microscopic colitis. Even when symptoms closely resemble anticancer drug or immune‐related colitis, drug‐induced colitis due to ...
Shinichi Maruyama +6 more
wiley +1 more source
The Antinociceptive Effects of Rosuvastatin in Chronic Constriction Injury Model of Male Rats
Basic and Clinical Neuroscience, 2018 Introduction: According to studies, statins possess analgesics and anti-inflammatory properties. In the present study, we examined the antinociceptive, anti-inflammatory and antioxidative effects of rosuvastatin in an experimental model of Chronic ...
Amin Hasanvand +6 more
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Sinus Pause and Cognitive Dysfunction: Diagnostic and Therapeutic Implications
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Bradyarrhythmia‐related cerebral hypoperfusion should be considered in elderly patients presenting with unexplained episodic cognitive decline, particularly when symptoms fluctuate or occur transiently. Prolonged rhythm monitoring may identify potentially treatable arrhythmic causes.
Mohd Aizuddin Mohd Zulastri +3 more
wiley +1 more source
A 32‐Year‐Old Man With an Cardiomyopathy
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT Scleredema is a sclerosing dermatosis of unknown etiology, characterized by non‐punctate, weakly infiltrated skin thickening and swelling, which can lead to the development of cardiomyopathy. Scleredema‐associated cardiomyopathy is at present poorly understood.
Yuting Zou, Shan Li, Tong Chen, Yi Li
wiley +1 more source