Results 71 to 80 of about 20,176 (178)
ABSTRACT Background High‐intensity statins are standard therapy after percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS), yet tolerability concerns and residual cardiovascular risk remain important challenges. Moderate‐intensity statin therapy combined with ezetimibe has emerged as a potential alternative, although its ...
Emad Uddin Sajid +12 more
wiley +1 more source
Pharmacokinetic Drug–Drug Interaction Potential of Oral Anticancer Drugs
Drug–drug interaction (DDI) management is critical for safe and effective use of oral anticancer drugs (OADs). Our study objectives were to (i) compile clinically relevant pharmacokinetic (PK) DDI mechanisms for OADs and (ii) assess the prevalence of PK potential DDIs (PDDIs) in patients with advanced solid cancers.
Fatimah Alhurayri +10 more
wiley +1 more source
ABSTRACT Background and Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD), causing cirrhosis and liver cancer, is prevalent worldwide. Analyses of internet searches for “fatty liver” and methods to raise MASLD awareness are needed. Methods We retrospectively analyzed co‐occurring terms with “fatty liver” and tracked search histories
Kaori Inoue +13 more
wiley +1 more source
Objective: to study the dose-dependent effect of rosuvastatin on blood lipids and lipoproteins (LP), endothelial functional activity, coagulation, and safety parameters in patients with hyperlipidemia (HLP) and hypertension after cerebral ischemic stroke
M. G Bubnova +3 more
doaj
ABSTRACT The detection of sweeteners in complex food matrices remains analytically challenging. The present study evaluates sandpaper spray mass spectrometry (SPS‐MS) as a rapid, direct, no‐sample‐preparation screening approach for sugar‐free candies and chewing gums.
Sarah Fernandes Coelho Viana +2 more
wiley +1 more source
APOE is widely recognized for its role in neurodegeneration and cardiovascular disease, but its different genotypes also influence body composition, affecting obesity, bone density, and muscle mass, through their central role in lipid transport and metabolism.
Miriam Frosina +5 more
wiley +1 more source
Dysregulated Lipid Metabolism in Hepatocellular Carcinoma: Mechanisms and Therapeutic Strategies
Dysregulated lipid metabolism facilitates hepatocellular carcinoma (HCC) development, progression, immunosuppressive tumor microenvironment (TME) formation, and therapeutic resistance. Notably, the patterns of lipid metabolism vary significantly among different types of HCC driven by various etiologies.
Yi Yi +4 more
wiley +1 more source
ABSTRACT Introduction Although drug shortages for outpatient chronic conditions commonly occur, population‐level data on how they impact patients' ability to refill prescriptions is scarce. We sought to identify distinct patterns of refill adherence following drug shortages and patient‐ and prescription‐level factors associated with adherence ...
Katie J. Suda +14 more
wiley +1 more source
Statin treatment: myths and reality
Aim. To assess effectiveness and tolerability of rosuvastatin treatment, as a part of primary and secondary cardiovascular prevention, in patients with high and very high cardiovascular risk and dyslipidemia.Material and methods.
L. A. Malay +5 more
doaj
ABSTRACT Rush Medical College implemented a new, integrated pre‐clerkship curriculum. Pharmacology was integrated with other basic sciences into a flipped, small‐group, case‐based structure. This report describes the main features of the pharmacology curriculum for pharmacology directors to have a template.
Brinda Desai Bradaric +3 more
wiley +1 more source

