Results 41 to 50 of about 22,635,235 (323)

Maintaining Momentum for Rotavirus Immunization in Africa during the COVID-19 Era: Report of the 13th African Rotavirus Symposium

Vaccines, 2022
The 13th African Rotavirus Symposium was held as a virtual event hosted by the University of Nairobi, Kenya and The Kenya Paediatric Association on 3rd and 4th November 2021.
Frederick N. Were, Khuzwayo C. Jere, George E. Armah, M. Jeffrey Mphahlele, Jason M. Mwenda, A. Duncan Steele   +5 more
doaj   +1 more source

The Epidemiology of Circulating Rotavirus Associated with Diarrhea in Egyptian Kids and Calves: A Review

Zoonoses, 2023
Acute gastroenteritis (AGE) induced by rotavirus has been a major disease burden in Egypt since 1981 when rotavirus was first reported in humans and calves.
Ahmed H Ghonaim, Mai G. Hopo, Noha H. Ghonaim, Yunbo Jiang, Qigai He, Wentao Li   +5 more
doaj   +1 more source

Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis.

New England Journal of Medicine, 2006
BACKGROUND The safety and efficacy of an attenuated G1P[8] human rotavirus (HRV) vaccine were tested in a randomized, double-blind, phase 3 trial. METHODS We studied 63,225 healthy infants from 11 Latin American countries and Finland who received two ...
G. Ruiz-Palacios, I. Pérez-Schael, F. Velázquez, H. Abate, T. Breuer, S. C. Clemens, B. Cheuvart, F. Espinoza, P. Gillard, B. Innis, Y. Cervantes, A. Linhares, Pio López, M. Macias-Parra, E. Ortega-Barria, Vesta L Richardson, D. M. Rivera-Medina, Luis Rivera, B. Salinas, N. Pavía-Ruz, J. Salmerón, R. Rüttimann, J. Tinoco, Pilar Rubio, E. Núñez, M. Guerrero, J. Yarzábal, Silvia Damaso, N. Tornieporth, X. Sáez-Llorens, Rodrigo Vergara, T. Vesikari, A. Bouckenooghe, R. Clemens, B. De Vos, M. O’Ryan   +35 more
semanticscholar   +1 more source

Rotavirus Pathogenicity

Virology, 1996
The pathogenicity of rotaviruses depends on multiple viral and host factors. In this review the evidence for the involvement of a number of viral genes in the ability to cause disease is presented. Different genes are of importance in different rotavirus-host systems: there is no single pathogenicity factor.
Burke, B, Desselberger, U
openaire   +3 more sources

Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine.

New England Journal of Medicine, 2006
BACKGROUND Rotavirus is a leading cause of childhood gastroenteritis and death worldwide. METHODS We studied healthy infants approximately 6 to 12 weeks old who were randomly assigned to receive three oral doses of live pentavalent human-bovine (WC3 ...
T. Vesikari, D. Matson, P. Dennehy, P. van Damme, M. Santosham, Zoe M. Rodriguez, M. Dallas, J. Heyse, Michelle G. Goveia, S. Black, H. Shinefield, C. Christie, S. Ylitalo, R. Itzler, M. Coia, Matthew T. Onorato, Ben A. Adeyi, G. Marshall, L. Gothefors, Dirk Campens, A. Karvonen, J. Watt, K. O'Brien, M. Dinubile, H. Clark, J. Boslego, P. Offit, Penny M Heaton   +27 more
semanticscholar   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Reduction in morbidity and mortality from childhood diarrhoeal disease after species A rotavirus vaccine introduction in Latin America : a review

Memorias do Instituto Oswaldo Cruz, 2011
Countries in Latin America were among the first to implement routine vaccination against species A rotavirus (RVA). We evaluate data from Latin America on reductions in gastroenteritis and RVA disease burden following the introduction of RVA vaccine ...
Rishi Desai, Lucia Helena de Oliveira, Umesh D Parashar, Benjamin Lopman, Jacqueline E Tate, Manish M Patel   +5 more
doaj   +1 more source

Rotavírus A em crianças de até três anos de idade, hospitalizadas com gastroenterite aguda em Campo Grande, Estado do Mato Grosso do Sul Rotavirus A among hospitalized infants, up to three years of age, with acute gastroenteritis in Campo Grande, State of Mato Grosso do Sul

Revista da Sociedade Brasileira de Medicina Tropical, 2007
Através da eletroforese em gel de poliacrilamida e do ensaio imunenzimático combinado para rotavírus e adenovirus, foram analisadas 380 amostras fecais de crianças com até 3 anos, hospitalizadas com diarréia aguda, entre maio de 2000 e janeiro de 2004 ...
Márcia Sueli Assis Andreasi, Sonia Maria Fernandes Batista, Inês Aparecida Tozetti, Cláudia Okanobo Ozaki, Mariana Menegusso Nogueira, Fabíola Souza Fiaccadori, Ana Maria Tavares Borges, Rodrigo Alessandro Togo Santos, Divina das Dores de Paula Cardoso   +8 more
doaj   +1 more source

A Novel Rotavirus Reverse Genetics Platform Supports Flexible Insertion of Exogenous Genes and Enables Rapid Development of a High-Throughput Neutralization Assay

Viruses, 2023
Despite the success of rotavirus vaccines, rotaviruses remain one of the leading causes of diarrheal diseases, resulting in significant childhood morbidity and mortality, especially in low- and middle-income countries. The reverse genetics system enables
Jiajie Wei, Scott Radcliffe, Amanda Pirrone, Meiqing Lu, Yuan Li, Jason Cassaday, William Newhard, Gwendolyn J. Heidecker, William A. Rose II, Xi He, Daniel Freed, Michael Citron, Amy Espeseth, Dai Wang   +13 more
doaj   +1 more source

Incidence of diarrhea caused by rotavirus infections in rural Zhengding, China: prospective, population-based surveillance.

, 2005
Rotavirus is the pathogen most commonly associated with severe gastroenteritis in young children in the People's Republic of China, yet there are few population-based data on the incidence of rotavirus infection. The present study investigated the burden
Wang, Xuan-Yi, Xu, Zhi-Yi, von Seidlein, Lorenz, Zhang, Ying-Lin, Zhao, Shou-Jun, Hao, Zhi-Yong, Han, Oak Pil, Kilgore, Paul, Xing, Zhan-Chun, Han, Chang-Quan, Ma, Jing-Chen, Chen, Ji-Chao, Clemens, John   +12 more
core   +1 more source