Results 11 to 20 of about 696,195 (244)
Established and new rotavirus vaccines: a comprehensive review for healthcare professionals. [PDF]
Hum Vaccin Immunother, 2022 Robust scientific evidence related to two rotavirus (RV) vaccines available worldwide demonstrates their significant impact on RV disease burden. Improving RV vaccination coverage may result in better RV disease control. To make RV vaccination accessible
Vetter V +4 more
europepmc +2 more sources
Real-world effectiveness of rotavirus vaccines, 2006-19: a literature review and meta-analysis. [PDF]
Lancet Glob Health, 2020 BACKGROUND Since licensure in 2006, rotavirus vaccines have been introduced in more than 100 countries. The efficacy of rotavirus vaccines is variable in settings with different child mortality levels. We did an updated review of the published literature
Burnett E, Parashar UD, Tate JE.
europepmc +2 more sources
Expert Review of Vaccines, 2018 Introduction: Numerous studies have shown that the oral rotavirus vaccines are less effective in infants born in low income countries compared to those born in developed countries.
Daniel E. Velasquez +2 more
doaj +2 more sources
Indian Journal of Medical Microbiology, 2006 Rotavirus, the most common cause of severe diarrhea and a leading cause of mortality in children, has been a priority target for vaccine development for the past several years. The first rotavirus vaccine licensed in the United States was withdrawn because of an association of the vaccine with intussusception.
europepmc +4 more sources
Current and new rotavirus vaccines. [PDF]
Curr Opin Infect Dis, 2019 Purpose of review As of 2019, four rotavirus vaccines have been prequalified by the WHO for use worldwide. This review highlights current knowledge regarding rotavirus vaccines available, and provides a brief summary of the rotavirus vaccine pipeline ...
Burke RM +4 more
europepmc +2 more sources
Rotavirus Vaccines: a story of success with challenges ahead [version 1; referees: 3 approved]
F1000Research, 2017 Approximately 40 years have passed since the discovery of the rotavirus and 10 years since the introduction and progressive dissemination of rotavirus vaccines worldwide.
Miguel O’Ryan
doaj +2 more sources
Leveraging Beneficial Off-Target Effects of Live-Attenuated Rotavirus Vaccines [PDF]
Vaccines, 2022 Following the introduction of live-attenuated rotavirus vaccines in many countries, a notable reduction in deaths and hospitalisations associated with diarrhoea in children
Prisca Benedicto-Matambo +11 more
doaj +2 more sources
Update on Early-Life T Cells: Impact on Oral Rotavirus Vaccines [PDF]
VirusesRotavirus infection continues to be a significant public health problem in developing countries, despite the availability of several vaccines. The efficacy of oral rotavirus vaccines in young children may be affected by significant immunological ...
Catherine Montenegro +2 more
doaj +2 more sources
Human Vaccines & Immunotherapeutics, 2021 In the decade since oral rotavirus vaccines (ORV) were recommended by the World Health Organization for universal inclusion in all national immunization programs, significant yet incomplete progress has been made toward reducing the burden of rotavirus ...
Benjamin Lee
doaj +2 more sources
Options for improving effectiveness of rotavirus vaccines in developing countries
Human Vaccines & Immunotherapeutics, 2017 Rotavirus gastroenteritis is a leading global cause of mortality and morbidity in young children due to diarrhea and dehydration. Over 85% of deaths occur in developing countries.
Marion S. Tissera +6 more
doaj +2 more sources