Rotenoids from the Roots of Vicia faba L. (Fabaceae): Structural Characterization, Cytotoxic Effects, and Molecular Docking. [PDF]
ABSTRACT The chemical study of the ethanolic extract from the roots of Vicia faba led to the isolation of two isoflavonoids, alfalone and 8‐O‐methylretusine, as well as a mixture of rotenoids, including clitoriacetal and clitoriacetal B, the latter of which is reported for the first time.
Sipoloni VM +8 more
europepmc +2 more sources
Confrontations of the Pathogenic Fungus Colletotrichum graminicola With a Biocontrol Bacterium or a Ubiquitous Fungus Trigger Synthesis of Secondary Metabolites With Lead Structures of Synthetic Fungicides. [PDF]
Introduction of biocontrol agents to agricultural environments creates microbial confrontations. In confrontations between a fungal maize pathogen and a biocontrol bacterium or a ubiquitous fungus, novel compounds with similarity to synthetic fungicides and substances putatively toxic to humans are formed, questioning consumer safety of biological ...
Fernando Devasahayam BR +3 more
europepmc +2 more sources
Potent antioxidant and genoprotective effects of boeravinone G, a rotenoid isolated from Boerhaavia diffusa. [PDF]
BACKGROUND AND AIMS: Free radicals are implicated in the aetiology of some gastrointestinal disorders such as gastric ulcer, colorectal cancer and inflammatory bowel disease.
Gabriella Aviello +8 more
doaj +1 more source
The discovery of novel botanical pesticides as a preferred alternative to synthetic pesticides is regarded as an environmentally friendly strategy, yet it remains a great challenge due to limited insights into the synthesis and accumulation of active ...
Ping Li +9 more
doaj +1 more source
Synergistic Activity of Deguelin and Fludarabine in Cells from Chronic Lymphocytic Leukemia Patients and in the New Zealand Black Murine Model. [PDF]
B-cell chronic lymphocytic leukemia (CLL) remains an incurable disease, and despite the improvement achieved by therapeutic regimes developed over the last years still a subset of patients face a rather poor prognosis and will eventually relapse and ...
Nerea Rebolleda +9 more
doaj +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander +165 more
wiley +1 more source
A review on invasive false indigo bush (Amorpha fruticosa L.): Nuisance plant with multiple benefits
Amorpha fruticosa L. represents an invasive plant causing a nuisance and degrading native biodiversity on a variety of wet and mesic habitats throughout the Northern Hemisphere. On the other hand, the plant species possesses numerous beneficial applications including phytochemical and biocoenotic uses, as well as ecosystem services.
Jasna Grabić +4 more
wiley +1 more source
Studying 400 T2DM patients without complication indicated: In T2DM patients without complication, the GPx and TAC levels decreased and the MDA level elevated. T2DM with neuropathy had lower levels of GSH, GPx, and TAC and higher levels of TOS, MDA, and OSI and a higher frequency of Keap1 AA genotype.
Farnaz Khalili +9 more
wiley +1 more source
Non‐small‐cell lung cancer (NSCLC) is the most common lung cancer and a major cause of cancer mortality worldwide. Deguelin plays a vital inhibitory role in NSCLC initiation and development. However, the downstream mechanism of deguelin‐suppressed metastasis of NSCLC cells is still not completely understood.
Guohua Lu +5 more
wiley +1 more source
Promising Potential of Lonchocarpus utilis against South American Myasis
Traditional medicine is especially important in the treatment of neglected tropical diseases because it is the way the majority of populations of affected countries manage primary healthcare.
Carmen X. Luzuriaga-Quichimbo +4 more
doaj +1 more source

