In Silico Research of New Therapeutics Rotenoids Derivatives against Leishmania amazonensis Infection [PDF]
Biology, 2022 Yearly, 1,500,000 cases of leishmaniasis are diagnosed, causing thousands of deaths. To advance in its therapy, we present an interdisciplinary protocol that unifies ethnobotanical knowledge of natural compounds and the latest bioinformatics advances to ...
Adrián Vicente-Barrueco +3 more
doaj +2 more sources
Anticholinesterase Activity of Methanolic Extract of Amorpha fruticosa Flowers and Isolation of Rotenoids and Putrescine and Spermidine Derivatives [PDF]
PlantsFive putrescine and spermidine derivatives (1–5) together with five rotenoids (6–10) were isolated from a methanolic extract of the flowers of A. fruticosa that displayed promising inhibition of 76.0 ± 1.9% for AChE and 90.0 ± 4.0% for BuChE at a ...
Dagmar Jankovská +8 more
doaj +2 more sources
Amorphigenin from Amorpha fruticosa L. Root Extract Induces Autophagy-Mediated Melanosome Degradation in mTOR-Independent- and AMPK-Dependent Manner [PDF]
Current Issues in Molecular Biology, 2022 In this study, we investigated the depigmentation effect of Amorpha fruticosa L. root extract (RE), an herbal medicine. A. fruticosa RE significantly induced depigmentation in α-MSH-treated B16F10 cells at noncytotoxic concentrations.
Ki Won Lee +10 more
doaj +2 more sources
Fabaceae Flavonoids Beyond the Commonplace: A Review of Chemical Diversity, Pharmacological Activities, Mass Spectrometric Profiling and In Silico Insights into Their Subclasses [PDF]
PlantsFabaceae family is recognized as a prolific flavonoid producer, including some unusual flavonoid skeletons. Although classic flavonoids have well-established biological properties in the literature, these unusual compounds remain underinvestigated. Based
Ana Rita Rodrigues de Almeida Silva Brilhante +9 more
doaj +2 more sources
New Class of Tyrosinase Inhibitors, Rotenoids, from Amorpha fruticosa [PDF]
ACS Omega, 2023 Si Won Moon +5 more
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Synthetic Studies on Rotenoids
Agricultural and Biological Chemistry, 1968 A general cyclization reaction to dehydrorotenoids has been developed. Dehydrorotenone (III) and dehydrodeguelin (IV) were obtained in high yield from methyl derrisate (Vb) and methyl deguelate (VIb), respectively, by treatment with sodium ethoxide.
Nobuji Nakatani, Masanao Matsui
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Phytomedicine Plus, 2022 Background: : The human body is almost 70% water and fluid imbalance has been a classic symptom of severe underlying conditions, i.e., hepatic disorders, kidney disorders, cardiovascular disease and inflammation. Boerhavia diffusa Linn.
Praveen Kumar Gaur +2 more
doaj +1 more source
Effect of Some Growth Regulators and Systemic Copper Complexes on Reducing Floral Malformation, Yield and Quality of "Alphonse" Mango (Mangifera indica L.) [PDF]
Arab Universities Journal of Agricultural Sciences, 2021 The present study was carried out during 2019 and 2020 seasons on Alphonse mango trees to evaluate the effect of some growth reg-ulators and systemic copper complexes on flo-ral malformation, yield and quality.
Abdelaty Aboelezz +3 more
doaj +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
British Journal of Pharmacology, Volume 180, Issue S2, Page S23-S144, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander +165 more
wiley +1 more source
A review on invasive false indigo bush (Amorpha fruticosa L.): Nuisance plant with multiple benefits
Ecology and Evolution, Volume 12, Issue 9, September 2022., 2022 Amorpha fruticosa L. represents an invasive plant causing a nuisance and degrading native biodiversity on a variety of wet and mesic habitats throughout the Northern Hemisphere. On the other hand, the plant species possesses numerous beneficial applications including phytochemical and biocoenotic uses, as well as ecosystem services.
Jasna Grabić +4 more
wiley +1 more source