Results 81 to 90 of about 3,562,701 (326)
FEBS Open Bio, EarlyView.We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source
Applications of polymers in intraocular drug delivery systems
Oman Journal of Ophthalmology, 2017 We are entering a new era of ophthalmic pharmacology where new drugs are rapidly being developed for the treatment of anterior and posterior segment of the eye disease.
Ali Mohammed Alhalafi
doaj +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source
Geodesic survey and modernization of a route as the task of optimization
Geodesy and Cartography, 2014 Inwentaryzacja istniejącej tras y wymaga wyznaczenia krzywej aproksymującej w wyniku optymalizacji realizowanej metodą najmniejszych kwadratów (TLSM). Analiza funkcji celu LSM wykazała, że jest ona kwadratem odległości Mahalanobisa w przestrzeni poprawek.
Nowak Edward
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FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Adaptive link-weight routing protocol using cross-layer communication for MANET [PDF]
, 2007 Routing efficiency is one of the challenges offered by Mobile Ad-hoc Networks (MANETs). This paper proposes a novel routing technique called Adaptive Link-Weight (ALW) routing protocol.
Al-Khwildi, AN +3 more
core +1 more source
Opportunistic Routing towards Mobile Sink Nodes in Bluetooth Mesh Networks
, 2021 Marcelo Paulon J. V. +2 more
openalex +1 more source
The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Electrification of Urban Transport. Basic Stages in Creating Electric Buses Fleet
Механика машин, механизмов и материалов, 2018 The paper is of an analytical nature and is devoted to the systematization of approaches that take place in the tasks of creating an urban fleet of electric buses.
Vladimir B. Algin
doaj
Transport, 2011 The article describes modelling a vehicle route to transport goods and discusses models for determining vehicle routes for a single depot and more vehicles. Above all, the paper defines a mathematical model for determining a vehicle route for more depots,
Jaroslav Kleprlík +2 more
doaj +1 more source