Results 131 to 140 of about 5,225,221 (383)

Routines of Riparian Women of the Amazon Region: Activities and Roles in the Family, at Work and in the Community

Interpersona: An International Journal on Personal Relationships, 2015
The aim of this study was to investigate the perception of the routines of women who live in Amazon riverside communities, identifying the roles and activities related to domestic work, açaí gathering and actions in community associations.
Neuzeli Maria de Almeida Pinto, Fernando Augusto Ramos Pontes, Simone Souza da Costa Silva   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Rotordynamic response analysis program [PDF]

, 1971
Computer routine is similar to Holzer's method in torsional vibration treatment, and Prohl's and Myklestad's approach in computing rotor deflection.
Shen, F. A.
core   +1 more source

Routine repeated echocardiographic monitoring of fetuses exposed to maternal anti-SSA antibodies: time to question the dogma [PDF]

, 2019
N. Costedoat‐Chalumeau, Nathalie Morel, Rebecca Fischer‐Betz, K. Lévesque, Alice Maltret, Munther A. Khamashta, Antonio Brucato   +6 more
openalex   +1 more source

Evaluating the impact of healthcare interventions using routine data

British medical journal, 2019
### What you need to know Interventions to transform the delivery of health and social care are being implemented widely, such as those linked to Accountable Care Organizations in the United States,1 or to integrated care systems in the UK.2 Assessing ...
G. Clarke, S. Conti, A. Wolters, A. Steventon   +3 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Extracting Lyapunov exponents from the echo dynamics of Bose-Einstein condensates on a lattice

, 2017
We propose theoretically an experimentally realizable method to demonstrate the Lyapunov instability and to extract the value of the largest Lyapunov exponent for a chaotic many-particle interacting system.
Andrei E. Tarkhov, Boris V. Fine, C. P. Slichter, E. N. Lorenz, E. Ott, F. Haake, J. C. Sprott, L. Amico, L. P. Pitaevskii, L. P. Pitaevskii, S. Wimberger, Sandro Wimberger   +11 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Job Polarization and Task-Biased Technological Change: Sweden, 1975–2005 [PDF]

This paper investigates the connection between the Swedish wage profile of net job creation and Autor, Levy, and Murnane’s (2003) proposed substitutability between routine tasks and technology. We first show that between 1975 and 2005, Sweden exhibited a
Adermon, Adrian, Gustavsson, Magnus
core