Results 71 to 80 of about 855,248 (321)

An Experimental Investigation of Hyperbolic Routing with a Smart Forwarding Plane in NDN

, 2016
Routing in NDN networks must scale in terms of forwarding table size and routing protocol overhead. Hyperbolic routing (HR) presents a potential solution to address the routing scalability problem, because it does not use traditional forwarding tables or
Aldecoa, Rodrigo, Gawande, Ashlesh, Krioukov, Dmitri, Lehman, Vince, Wang, Lan, Zhang, Beichuan, Zhang, Lixia   +6 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Self-routing lowest common ancestor networks [PDF]

, 1992
Multistage interconnection networks (MIN's) allow communication between terminals on opposing sides of a network. Lowest Common Ancestor Networks (LCAN's) [1] have switches capable of connecting bi-directional links in a permutation pattern that ...
Chien, Chi-Kai, Scherson, Isaac D.
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Performance Optimization of MANET Networks through Routing Protocol Analysis

Computers, 2020
A Mobile Ad Hoc Network (MANET) protocol requires proper settings to perform data transmission optimally. To overcome this problem, it is necessary to select the correct routing protocol and use the routing protocol’s default parameter values. This study
Tri Kuntoro Priyambodo, Danur Wijayanto, Made Santo Gitakarma   +2 more
doaj   +1 more source

Route masters [PDF]

Current Biology, 2007
A new study reveals that turtles stick closely to previous tracks between breeding and foraging sites, offering new potential to protect these animals at sea. Nigel Williams reports.
openaire   +2 more sources

The transhumance route of Pithoragarh: A cultural route?

Environmental Challenges, 2021
A cultural route represents a spatial link between different cultural groups, which co-influenced their mutual development, also enriched their relationship with the natural environment, resulting in a vast body of knowledge. First recognized on a world platform in 1993 by UNESCO, the concept is on its evolutionary stage, and there are several ...
Ram Sateesh Pasupuleti, Samiksha Srichandan, Anindya J. Mishra   +2 more
openaire   +3 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

An improved largest gap routing heuristic for order picking [PDF]

, 2012
The largest-gap policy is a routing heuristic for order picking systems. In this paper we develop an improved largest gap routing method. A simulation approach is used to demonstrate the superior performance of the improved largest gap routing over ...
Limère, Veronique, Liu, Jinping, Van Landeghem, Hendrik   +2 more
core   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source