Results 161 to 170 of about 59,105 (258)

Detection of a Target Nucleic Acid by Ligation‐Assisted Fluorescence Enhancement of a Peptide Nucleic Acid (PNA) Twin Probe via Disulfide Binding

Biopolymers, Volume 117, Issue 4, July 2026.
Target‐induced disulfide ligation of PNA twin probes promotes pyrene excimer formation for nucleic acid detection. ABSTRACT The development of methods for detecting specific nucleic acids is important for early diagnosis and treatment of diseases at the genetic level.
Yutaka Ouchi, Koki Ishii, Yumiko Sato, Yoshitane Imai, Hideo Matsui, Takashi Ohtsuki, Yoshiyuki Hakata, Hajime Shigeto, Shohei Yamamura, Mizuki Kitamatsu   +9 more
wiley   +1 more source

Validated RP-HPLC-UV Method for Simultaneous Quantification of Aminophenazone, Dipyrine, and Chlorpheniramine Maleate in Pharmaceutical Formulations Considering Dipyrine Decomposition. [PDF]

Int J Anal Chem
Hasan MA, Azmi S, Tabassum T, Sumit E, Gafur A, Helal N.   +5 more
europepmc   +1 more source

Chiral separation by RP-HPLC

, 2019
openaire   +2 more sources

DETERMINATION OF ETODOLAC BY RP-HPLC METHOD

International Research Journal Of Pharmacy, 2020
Vaibhav Gulabrao Bhamare, Ravindra K Kamble   +1 more
openaire   +1 more source

A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction

Biotechnology and Bioengineering, Volume 123, Issue 7, Page 1836-1870, July 2026.
ABSTRACT In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically complex. This study presents a modular mechanistic model of the IVT process to advance scientific understanding ...
Keqi Wang, Keilung Choy, Eli Reiser, Jinxiang Pei, Hua Zheng, Aparajita Dasgupta, Fuqiang Cheng, Guogang Dong, Bhanu Chandra Mulukutla, Joshua Mannheimer, Carolyn Huang, Hooman Farsani, Wei Xie   +12 more
wiley   +1 more source

Research note: Application and validation of RP-HPLC for quantifying ovomucoid, lysozyme, ovotransferrin, and ovalbumin in commercial pasteurized egg white. [PDF]

Poult Sci
Sousa I, Visentin E, Sabbadin S, Pozza M, Birolo M, De Marchi M, Niero G.   +6 more
europepmc   +1 more source

UPLC‐QTOF‐MS/MS and Antifungal Activity of a Fraction Enriched in Saponins From Sarcomphalus joazeiro Against Candida spp

Biomedical Chromatography, Volume 40, Issue 7, July 2026.
ABSTRACT The development of antifungal resistance is a complex process that involves the interaction between hosts, drugs, and microbial factors, all of which contribute to therapeutic ineffectiveness. For this reason, studies on natural products as possible therapeutic alternatives are increasingly necessary in order to gain a better understanding of ...
Ana Raquel Pereira da Silva, Maria do Socorro Costa, Nara Juliana Santos Araújo, Gabriel Gonçalves Alencar, Talysson Felismino Moura, Victor Juno Alencar Fonseca, Antônia Thassya Lucas dos Santos, Maria Flaviana Bezerra Morais‐Braga, Erlânio Oliveira de Souza, Josean Fechine Tavares, Paulo Riceli Vasconcelos Ribeiro, Jacqueline Cosmo Andrade‐Pinheiro, Henrique Douglas Melo Coutinho   +12 more
wiley   +1 more source

QbD-driven RP-HPLC method for the simultaneous analysis of dihydropyridines calcium channel blockers in pharmaceuticals. [PDF]

BMC Chem
Horyn M, Piponski M, Kryskiw L, Rezk MR, Zarivna N, Korobko D, Logoyda L.   +6 more
europepmc   +1 more source

A living biobank of sarcoma patient‐derived cell cultures reveals multi‐omic and functional insights that capture disease heterogeneity

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Preclinical models for sarcoma that preserve tumour biology are urgently needed to advance mechanistic understanding and functional precision oncology. 29 early‐passage patient‐derived sarcoma cell (PDC) cultures from 19 patients, representing 11 sarcoma subtypes were established and extensively characterized.
Stefanie Gijsels, Suzanne Fischer, David Creytens, Sándor Dedeyne, Felix De Vuyst, Cláudio Pinheiro, Fleur Cordier, Sarah‐Lee Bekaert, Nadine Van Roy, Kaat Durinck, Jarne Pauwels, Kris Gevaert, Pieter Mestdagh, Jo Vandesompele, Pekka Rappu, Jyrki Heino, An Hendrix, Gabrielle H. van Ramshorst, Gwen Sys, Olivier De Wever   +19 more
wiley   +1 more source

Breakthrough RP-HPLC strategy for synchronous analysis of pyridine and its degradation products in powder for injection using quality metrics. [PDF]

Sci Rep
Al-Wasidi AS, Katamesh NS, Alminderej FM, Saleh SM, Ahmed HA, Mohamed MA.   +5 more
europepmc   +1 more source