Results 11 to 20 of about 561,328 (285)

Development and Validation of an RP-HPLC-PDA Method for Determination of Paracetamol, Caffeine and Tramadol Hydrochloride in Pharmaceutical Formulations

Pharmaceuticals, 2021
Paracetamol (acetaminophen) (PAR), caffeine (CAF) and tramadol hydrochloride (TRA) are important drugs widely used for many clinical purposes. Determination of their contents is of the paramount interest.
F. J. Pereira, A. Rodríguez-Cordero, R. López, L. C. Robles, A. Aller   +4 more
semanticscholar   +1 more source

Determination of Ascorbic Acid Content using the Reverse Phase–High Performance Liquid Chromatography (RP-HPLC) Method

Al-Kimia, 2020
A method of reverse phase-high performance liquid chromatography (RP-HPLC) was evaluated in ascorbic acid determination. The determination was conducted at optimum conditions for RP-HPLC method, including ethanol as mobile phase, flow velocity of 0.8 mL ...
Nurul Ismillayli, Dhony Hermanto, I. G. A. Sri Andayani, Ruru Honiar, Ulul Khairi Zuryati, Baiq Mariana, Linda Marta Shofiyana   +6 more
doaj   +1 more source

Physical characteristics comparison between maytansinoid-based and auristatin-based antibody-drug conjugates

Exploration of Targeted Anti-tumor Therapy, 2021
Aim: Direct analytical comparison of two major drug-linkers in the antibody-drug conjugate (ADC) field was conducted. Methods: Four different analytical methods [AlogP calculation, reverse phase (RP) high-performance liquid chromatography (HPLC; RP ...
Tomohiro Fujii, Calliste Reiling, Colette Quinn, Michal Kliman, Brian A. Mendelsohn, Yutaka Matsuda   +5 more
doaj   +1 more source

Design of Experiment Centered Multivariate Optimization Strategy for RP-HPLC Method to Quantitate Retapamulin in Topical Cream and Microemulsion [PDF]

Pharmaceutical Sciences, 2021
Background: Retapamulin is the first pleuromutilin antibacterial approved for the treatment of impetigo. The objective of the current research was to utilize the design of experiments approach for development and optimization of robust RP-HPLC method for
Rashmin Bharat Patel, Nishant Patel, Mrunali R Patel   +2 more
doaj   +1 more source

Chemometric Classification of Cocoa Bean Shells Based on Their Polyphenolic Profile Determined by RP-HPLC-PDA Analysis and Spectrophotometric Assays

Antioxidants, 2021
The cocoa bean shell (CBS), a byproduct from the cocoa industry, was recently proposed as a functional and low-cost ingredient, mainly because of its content in polyphenols.
O. Rojo-Poveda, G. Zeppa, I. Ferrocino, C. Stévigny, L. Barbosa-Pereira   +4 more
semanticscholar   +1 more source

Application of HPLC-QQQ-MS/MS and New RP-HPLC-DAD System Utilizing the Chaotropic Effect for Determination of Nicotine and Its Major Metabolites Cotinine, and trans-3′-Hydroxycotinine in Human Plasma Samples

Molecules, 2022
The routine techniques currently applied for the determination of nicotine and its major metabolites, cotinine, and trans-3′-hydroxycotinine, in biological fluids, include spectrophotometric, immunoassays, and chromatographic techniques.
Jacek Baj, Wojciech Flieger, Dominika Przygodzka, Grzegorz Buszewicz, Grzegorz Teresiński, Magdalena Pizoń, Ryszard Maciejewski, Jolanta Flieger   +7 more
doaj   +1 more source

Analytical Method Development and Validation and Forced Degradation Stability-Indicating Studies of Favipiravir by RP-HPLC and UV in Bulk and Pharmaceutical Dosage Form

Journal of Pharmaceutical Research International, 2021
Aims: To develop and validate a new, simple, rapid, precise, and accurate An Eco-friendly RP-HPLC and UV-Method Development and Validation for an estimation of Favipiravir in Bulk and pharmaceutical dosage form followed by Forced Degradation Studies ...
S. Ali, Lajporiya Mobina, Manjra Mehfuza, Patel Seema, Aejaz Ahmed, G. J. Khan   +5 more
semanticscholar   +1 more source

Development and Validation of RP-HPLC Method for the Determination of Dexrabeprazole Sodium

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2021
A rapid and simple liquid chromatographic method was developed for the quantitative determination of dexrabeprazole sodium in the tablet dosage form. The reverse-phase chromatographic analysis was carried out by using a C-18 column.
Semra Yılmazer Keskin, Cihansel Unlu, Ebru Nurdan Şentürk   +2 more
doaj   +1 more source

Determination of the lipophilicity of 2'-hydroxychalcones by RP HPLC method [PDF]

Hemijska Industrija, 2016
Lipophilicity of twelve synthesized chalcones, whose ring B is a ortho, meta or para monosubstituted with alkyl, oxyalkyl groups or halogens was determined by reverse phase liquid chromatography, using octadecyl-functionalized (RP-18) silica gel
Bašić Jasmina V., Ivković Branka M., Stevanović Slavica, Lazarević Anđelka, Vujić Zorica B.   +4 more
doaj   +1 more source

Development and validation of an rp-hplc method for simultaneous determination of Ramipril and Amlodipine in tablets

Journal of Pharmaceutical Analysis, 2013
An rp-hplc method for the simultaneous determination of Ramipril (RP) and Amlodipine (AL) in tablets was developed and validated by Chinese Pharmacopoeia 2010. The linearity of the proposed method was investigated in the range of 0.01–0.25 mg/mL (r2=0.
Shi-Ying Dai, Shi-Ting Qiu, Wei Wu, Chun-Mei Fu   +3 more
doaj   +1 more source