Results 11 to 20 of about 67,204 (291)

Determination of the lipophilicity of 2'-hydroxychalcones by RP HPLC method [PDF]

open access: yesHemijska Industrija, 2016
Lipophilicity of twelve synthesized chalcones, whose ring B is a ortho, meta or para monosubstituted with alkyl, oxyalkyl groups or halogens was determined by reverse phase liquid chromatography, using octadecyl-functionalized (RP-18) silica gel
Bašić Jasmina V.   +4 more
doaj   +1 more source

Rational Design of a Facially Coordinating P,N,N Ligand for Manganese‐Catalysed Enantioselective Hydrogenation of Cyclic Ketones

open access: yesAngewandte Chemie International Edition, Volume 62, Issue 3, January 16, 2023., 2023
A Mn catalyst has been rationally redesigned to repel sp3hybridised substituents while attracting sp2 substituents, and hence enable enantioselective hydrogenation of cyclic ketones. DFT calculations enable a robust prediction of the level of enantiocontrol across a range of substrates.
Conor L. Oates   +3 more
wiley   +1 more source

The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis

open access: yesAngewandte Chemie International Edition, Volume 62, Issue 3, January 16, 2023., 2023
The cytochrome P450 enzyme AbyV catalyses a key epoxidation in the final stages of the biosynthesis of the spirotetronate antibiotic abyssomicin C. Combining structural and computational data with a 13C labelling strategy was found to be a powerful approach to interrogate the biotransformation and determine the precise function of the enzyme.
Andrew J. Devine   +13 more
wiley   +1 more source

ANALYSIS OF INSECTICIDE GELS CONTAINING FIPRONIL BY RP HPLC

open access: yesТонкие химические технологии, 2018
The article considers fipronil determination by the method of RP HPLC in isocratic mode with ultraviolet detection at 280 nm. The analysis of insecticidal gels containing fipronil and fipronil mixture with chlorpyriphos was carried out.
L. A. Nosikova, A. N. Kochetov
doaj   +1 more source

Phosphorylated calix[4,8]arenes improve the RP HPLC separation of benzene derivatives

open access: yesЖурнал органічної та фармацевтичної хімії, 2020
Aim. To study the effect of 5,11,17,23-tetrakis(diisopropoxyphosphonyl)-25,26,27,28-tetrapropoxycalix[4]arene and oсtаkis(diethoxyphosphoryloxy)-tert-butylcalix[8]аrene additives to the MeCN – H2O mobile phase (86:14) on the selectivity of the separation
Olga I. Kalchenko   +2 more
doaj   +1 more source

The Determination of Food Dyes in Vitamins by RP-HPLC

open access: yesMolecules, 2016
Reversed-phase high performance liquid chromatography (RP-HPLC) for the determination of five synthetic food dyes (Quinoline Yellow E104, Sunset Yellow E110, Ponceau 4R E124, Tartrazine E102 and Carmine E120) in vitamins was used. The dyes were analyzed within 10 min using a column with stationary phase C 18 (250 mm × 4.6 mm, 5 μm) at 40 °C with ...
Miroslava Smrčová   +2 more
openaire   +4 more sources

Benefits and Limitations of Lab-on-a-Chip Method over Reversed-Phase High-Performance Liquid Chromatography Method in Gluten Proteins Evaluation

open access: yesJournal of Chemistry, 2015
RP-HPLC (reversed-phase high-performance liquid chromatography) is widely used to determine the amounts of the different gluten protein types. However, this method is time-consuming, especially at early stages of wheat breeding, when large number of ...
Dragan Živančev   +6 more
doaj   +1 more source

Determination of doxazosin mesylate in tablets by RP-HPLC

open access: yesIndian Journal of Pharmaceutical Sciences, 2011
A simple, precise and rapid RP-HPLC method was developed for the determination of doxazosin mesylate in pharmaceutical formulations. The method was carried out on a Chromolith RP-C(18) column using a mixture of potassium phosphate buffer and methanol (40:60 v/v) and detection was done at 251 nm. The linearity range was 1-5 μg/ml.
Avinash K. Seth   +4 more
openaire   +4 more sources

Modified aqueous mobile phases: A way to improve retention behavior of active pharmaceutical compounds and their impurities in liquid chromatography

open access: yesJournal of Chromatography Open, 2022
Most commonly used analytical technique for determination of active pharmaceutical ingredients and their impurities in quality control throughout all phases of drug research, development and manufacture is definitely reversed-phase high performance ...
Nevena Djajić   +7 more
doaj  

Estudo comparativo de procedimentos experimentais e computacionais para cálculo da lipofilia molecular

open access: yesSaúde & Tecnologia, 2011
Introdução – A lipofilia é uma das propriedades físico-químicas que mais influencia a capacidade de uma molécula se movimentar através de compartimentos biológicos.
Gonçalo Clemente
doaj   +1 more source

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