Results 41 to 50 of about 59,105 (258)

π‐Extended COUPY Fluorophores for Targeted Near‐Infrared Fluorescence and Lifetime Imaging in Live Cells

Angewandte Chemie, EarlyView.
π‐Extended COUPY dyes, obtained by vinylogation of coumarin‐based COUPY scaffolds, shift absorption, and emission deep into the NIR region while preserving compactness and synthetic accessibility. These bright, photostable dyes enable live‐cell imaging, FLIM, and site‐specific peptide conjugation, offering a modular platform for targeted bioimaging and
Diego Abad‐Montero, Manel Bosch, Rodrigo Garcés‐Castellanos, Michael Q. Schottenhamel, Sergio Pedraza‐Arevalo, Alejandro Ibáñez‐Costa, Justo P. Castaño, Tania García‐Becerra, Elena Rebollo, Marta E. Alberto, Antonio Francés‐Monerris, Vicente Marchán   +11 more
wiley   +2 more sources

Reverse Phase High-performance Liquid Chromatography: A Comprehensive Review of Principles, Instrumentation, Analytical Procedures, and Pharmaceutical Applications

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine
A popular analytical method in the domains of material sciences, pharmacology, biology, the environment, food, cosmetics, and forensics is reverse phase high-performance liquid chromatography (RP-HPLC). Both polar and nonpolar molecules may be separated,
Suman Basak, Piyali Das
doaj   +1 more source

Concept of ecologically acceptable chromatographic methods: Case study on the separation of dronedarone hydrochloride and its degradation products [PDF]

Arhiv za farmaciju
Recently, concern about the environmental impact of drug analysis methods has increased significantly. Reversed-phase high-performance liquid chromatography (RP-HPLC), the predominant technique in drug analysis, relies heavily on organic solvents such as
Đajić Nevena, Krmar Jovana, Stojanović Jevrem, Svrkota Bojana, Otašević Biljana, Malenović Anđelija, Protić Ana   +6 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Quality by design based ecofriendly HPLC analytical method for simultaneous quantification of erastin and lenalidomide in mesoporous silica nanoparticles

Scientific Reports
The aims of this work to optimize and validate a RP-HPLC method to quantify erastin (ERT) and lenalidomide (LND) in mesoporous silica nanoparticles (MSNs). The Design of Experiments (DoE) strategy optimized the RP-HPLC method.
Ashutosh Gupta, S. P. Rachana, Sudheer Moorkoth, Namdev Dhas   +3 more
doaj   +1 more source

A single robust stability-indicating RP-HPLC analytical tool for apigenin quantification in bulk powder and in nanoliposomes: a novel approach

Future Journal of Pharmaceutical Sciences, 2021
Background Apigenin (4′, 5, 7-trihydroxyflavone), a flavonoid, is present usually in fruits and vegetables possessing numerous biological properties like antioxidant, anti-viral, antibacterial, anti-inflammatory, and chemoprevention activity.
Priya Shetti, Sunil S. Jalalpure
doaj   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

Advanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao, Jennifer Michel, Eline Lorer, Markus Weinmann, Jacques Le Gouis, Claire Léon, Sibille Perrochon, David Alvarez, Vincent Leemans, Iñaki Balanzategui Guijarro, Jordi Moya Laraño, Sara Sánchez Moreno, Symanczik Sarah, Waibel Matthias, Hervé Vanderschuren, Cécile Thonar, Pierre Delaplace, Dominique Van Der Straeten   +17 more
wiley   +1 more source

PENENTUAN WAKTU MATI MEMANFAATKAN DERET HOMOLOG ALKILPARABEN PADA RP-HPLC DALAM SISTEM PELARUT METANOL/AIR

Jurnal Natural, 2016
Penelitian ini dalam rangka pengembangan dan aplikasi metode penentuan waktu mati (t0) pada Kromatografi Cair dari yang telah pernah dan berhasil diterapkan di GC.
Mahmudi ., Saiful ., Khairan ., Rinaldi Idroes   +3 more
doaj   +2 more sources