Results 41 to 50 of about 97,740 (305)

Quality by design based ecofriendly HPLC analytical method for simultaneous quantification of erastin and lenalidomide in mesoporous silica nanoparticles

open access: yesScientific Reports
The aims of this work to optimize and validate a RP-HPLC method to quantify erastin (ERT) and lenalidomide (LND) in mesoporous silica nanoparticles (MSNs). The Design of Experiments (DoE) strategy optimized the RP-HPLC method.
Ashutosh Gupta   +3 more
doaj   +1 more source

Reverse Phase High-performance Liquid Chromatography: A Comprehensive Review of Principles, Instrumentation, Analytical Procedures, and Pharmaceutical Applications

open access: yesJournal of Preventive, Diagnostic and Treatment Strategies in Medicine
A popular analytical method in the domains of material sciences, pharmacology, biology, the environment, food, cosmetics, and forensics is reverse phase high-performance liquid chromatography (RP-HPLC). Both polar and nonpolar molecules may be separated,
Suman Basak, Piyali Das
doaj   +1 more source

A validated RP-HPLC method for simultaneous determination of propranolol and valsartan in bulk drug and gel formulation

open access: yesJournal of Pharmacy and Bioallied Sciences, 2013
Objective: A simple, precise, and stability indicating high performance liquid chromatography (HPLC) method was developed and validated for the simultaneous determination of propranolol hydrochloride and valsartan in pharmaceutical dosage form. Materials
Syed Sarim Imam   +4 more
doaj   +1 more source

Separation of Nucleic Acids by Ion Pair Reversed Phase High Performance Liquid Chromatography (IP RP HPLC) [PDF]

open access: yes, 2019
Ion-pair reversed-phase high performance liquid chromatography (IP RP HPLC) is shown to be an effective method to reliably analyze DNA. IP RP HPLC is a much faster and safer alternative to conventional methods of DNA separation and quantification.
Bestwick, Megan, McLeod, Zachary
core   +1 more source

Fluorescent Nanosensor for Indole‐3‐Propionic Acid Detection in Gut Health Monitoring

open access: yesAdvanced Healthcare Materials, EarlyView.
This work introduces a fluorescent nanosensor system with two optical modalities for detection of indole‐3‐propionic acid (IPA) gut metabolite: (1) blue‐emitting cationic conjugated polyelectrolyte (CP3) and (2) near‐infrared (NIR)‐emitting CP3‐wrapped single‐walled carbon nanotube (SWNT).
Mervin Chun‐Yi Ang   +15 more
wiley   +1 more source

BNB/NBN‐Phenalenyl‐2'‐deoxyuridines as a Fluorophore–Quencher Pair in DNA

open access: yesAngewandte Chemie, EarlyView.
Two BN‐chromophore‐extended nucleosides containing electronically complementary BNB‐ and NBN‐doped phenalenyls were synthesised and incorporated into deoxyribonucleic acid (DNA) oligonucleotides. These chromophores act as an efficient fluorophore–quencher pair under aqueous conditions.
Sarah Lutz   +6 more
wiley   +2 more sources

PENENTUAN WAKTU MATI MEMANFAATKAN DERET HOMOLOG ALKILPARABEN PADA RP-HPLC DALAM SISTEM PELARUT METANOL/AIR

open access: yesJurnal Natural, 2016
Penelitian ini dalam rangka pengembangan dan aplikasi metode penentuan waktu mati (t0) pada Kromatografi Cair dari yang telah pernah dan berhasil diterapkan di GC.
Mahmudi .   +3 more
doaj   +2 more sources

Method operable design region for robust RP-HPLC analysis of pioglitazone hydrochloride and teneligliptin hydrobromide hydrate: incorporating hybrid principles of white analytical chemistry and design of experiments

open access: yesFuture Journal of Pharmaceutical Sciences, 2023
Background A combination of pioglitazone hydrochloride with teneligliptin hydrobromide hydrate is used to treat type-2 diabetes. Several chromatographic techniques have been described in the literature for determination of each of these medications ...
Pintu Prajapati   +3 more
doaj   +1 more source

Quantification of DNA Products Using Ion-Pair Reverse Phase Liquid Chromatography [PDF]

open access: yes, 2017
The transcription of DNA via RNA polymerases is a fundamental process in cellular systems. In eukaryotic cells, we observe transcription in the nucleus (via genomic DNA) as well as in the mitochondria (via mitochondrial DNA).
Bestwick, Megan, Wienkers, Henry
core   +1 more source

Yeast Rrp8p, a novel methyltransferase responsible for m1A 645 base modification of 25S rRNA [PDF]

open access: yes, 2012
Ribosomal RNA undergoes various modifications to optimize ribosomal structure and expand the topological potential of RNA. The most common nucleotide modifications in ribosomal RNA (rRNA) are pseudouridylations and 2'-O methylations (Nm), performed by H ...
Entian, Karl-Dieter   +5 more
core   +1 more source

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