Results 31 to 40 of about 59,105 (258)
Saúde & Tecnologia, 2011 Introdução – A lipofilia é uma das propriedades físico-químicas que mais influencia a capacidade de uma molécula se movimentar através de compartimentos biológicos.
Gonçalo Clemente
doaj +1 more source
Siriraj Medical Journal, 2020 Objective: We tested the possibility of the use of reverse-phase high performance liquid chromatography (RP-HPLC), a sensitive, simple and cost effective technique, for evaluation of global DNA methylation alteration in stem cells.
Tatsanee Phermthai +6 more
doaj
Angewandte Chemie, EarlyView.Epimer discrimination remains challenging due to subtle NMR differences. Here, we propose a methodology based on 13C‐RCSA and RDC anisotropic parameters, enabling the assignment of two flexible tetraprenyltoluquinol epimers (1a and 1b) with remote stereoclusters.
Juan Carlos C. Fuentes‐Monteverde +6 more
wiley +2 more sources
Saúde & Tecnologia, 2015 Background – The lipophilicity is one of the physicochemical properties that most influences the ability of a molecule to move through biological compartments.
Gonçalo Clemente
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Frontiers in Plant Science, 2020 The wheat gliadins are a complex group of flour proteins that can trigger celiac disease and serious food allergies. As a result, mutation breeding and biotechnology approaches are being used to develop new wheat lines with reduced immunogenic potential.
You-Ran Jang +10 more
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Angewandte Chemie, EarlyView.A nanopore composed of transmembrane peptides and a DNA scaffold that assists peptide assembly was constructed. By employing peptides containing the unnatural amino acid 2‐aminoisobutyric acid (Aib), which promotes loose packing between helices, a large‐diameter nanopore was achieved.
Zugui Peng +3 more
wiley +2 more sources
Molecules, 2022 The study aimed to develop a new reverse-phase high-performance liquid chromatography (RP-HPLC) method with diode array detection (DAD) detection for simultaneous estimation of escitalopram (EST) and clonazepam (CZP) in tablet dosage forms with a quality
Ahmed I. Foudah +5 more
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RP-HPLC Method for the Determination and Quantification of Artesunate
Journal of Chromatographic Science, 2020 Abstract A simple, rapid and cost-effective reverse phase high-performance liquid chromatographic (RP-HPLC) method was developed for the quantification of artesunate. C18 Promosil (ODS, 150 × 4.6 mm, 5 μm) column was used as stationary phase to separate the drug.
Muhammad Asad Saeed +3 more
openaire +2 more sources
Angewandte Chemie, EarlyView.All three diastereoisomers of an esterase‐sensitive phosphotriester dCDN prodrug demonstrate improved activity. The (Rp,Rp) diastereoisomer shows the highest activity with an EC50 of 1.7 nM in STING activation and displays the most pronounced antitumor activity via intravenous administration, significantly suppressing tumor proliferation, extending the
Zhiqiang Xie +14 more
wiley +2 more sources
RP-HPLC Analysis and Antidiabetic Activity of
Natural Product Communications, 2010 1,2,6,8-Tetrahydroxyxanthone (SR1) and 2,8-dihydroxy-1,6-dimethoxyxanthone (SR2) have been qualitatively and quantitatively determined in leaves and rhizomes of Swertia paniculata. The methanol extracts were analyzed on a C 18 column using MeOH and H 2 O
Jagmohan S. Negi +3 more
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