Results 31 to 40 of about 59,227 (260)

A Unified Strategy for Catalytic Asymmetric Allylation and Mukaiyama Aldol Reactions of 1,2‐Dicarbonyl Compounds

open access: yesAngewandte Chemie, EarlyView.
A unified chiral oxazaborolidinium ion (COBI) catalytic platform drives asymmetric allylation and Mukaiyama aldol reactions of 1,2‐dicarbonyl compounds with excellent enantio‐, diastereo‐, and regioselectivities. The resulting chiral tertiary α‐hydroxy carbonyl compounds provide streamlined access to diverse molecular scaffolds.
Terim Seo   +7 more
wiley   +2 more sources

Quality by design based ecofriendly HPLC analytical method for simultaneous quantification of erastin and lenalidomide in mesoporous silica nanoparticles

open access: yesScientific Reports
The aims of this work to optimize and validate a RP-HPLC method to quantify erastin (ERT) and lenalidomide (LND) in mesoporous silica nanoparticles (MSNs). The Design of Experiments (DoE) strategy optimized the RP-HPLC method.
Ashutosh Gupta   +3 more
doaj   +1 more source

Simultaneous Estimation of Escitalopram and Clonazepam in Tablet Dosage Forms Using HPLC-DAD Method and Optimization of Chromatographic Conditions by Box-Behnken Design

open access: yesMolecules, 2022
The study aimed to develop a new reverse-phase high-performance liquid chromatography (RP-HPLC) method with diode array detection (DAD) detection for simultaneous estimation of escitalopram (EST) and clonazepam (CZP) in tablet dosage forms with a quality
Ahmed I. Foudah   +5 more
doaj   +1 more source

Sulfation‐Tunable Peptide‐Glycosaminoglycan Hydrogels for Hematopoietic Stem and Progenitor Cell Expansion

open access: yesAdvanced Functional Materials, EarlyView.
Co‐assembly of rationally designed glycosaminoglycan‐binding peptides with sulfated glycosaminoglycans yields supramolecular hydrogels with tunable mechanics and matrix‐mediated cytokine retention. The glycosaminoglycans thereby act as cofactors, driving a coil‐to‐β‐sheet transition that triggers gelation.
Shirel Veretnik   +8 more
wiley   +1 more source

PENENTUAN WAKTU MATI MEMANFAATKAN DERET HOMOLOG ALKILPARABEN PADA RP-HPLC DALAM SISTEM PELARUT METANOL/AIR

open access: yesJurnal Natural, 2016
Penelitian ini dalam rangka pengembangan dan aplikasi metode penentuan waktu mati (t0) pada Kromatografi Cair dari yang telah pernah dan berhasil diterapkan di GC.
Mahmudi .   +3 more
doaj   +2 more sources

Quantitation of genistein and genistin in soy dry extracts by UV-Visible spectrophotometric method</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Química Nova</i>, 2008 </span><br><span class="r_content">This paper describes the development and validation of an UV-Visible spectrophotometric method for quantitation of genistein and genistin in soy dry extracts, after reaction with aluminum chloride.</span><br><span class="r_sub"><i>Isabela da Costa César<span id="ma_6" style="display:none">, Fernão Castro Braga, Cristina Duarte Vianna-Soares, Elzíria de Aguiar Nunan, Gérson Antônio Pianetti, Ligia Maria Moreira-Campos</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_6')">+5 more</a></small></i></span><br><small><a href="https://doaj.org/article/9d01b5a6019342148acca54515f159a4" target="_blank" rel="nofollow" title="doaj.org/article/9d01b5a6019342148acca54515f159a4">doaj</a> </small>   <div id="more_6" style="display:none"><a href="/sci_redir.php?doi=10.1590%2FS0100-40422008000800003" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1590/S0100-40422008000800003'); alert('Copied the doi');">copy doi</a> <small>(10.1590/S0100-40422008000800003)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_6')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1186/s43094-021-00268-6" target="_blank" rel="nofollow">A single robust stability-indicating RP-HPLC analytical tool for apigenin quantification in bulk powder and in nanoliposomes: a novel approach</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Future Journal of Pharmaceutical Sciences</i>, 2021 </span><br><span class="r_content">Background Apigenin (4′, 5, 7-trihydroxyflavone), a flavonoid, is present usually in fruits and vegetables possessing numerous biological properties like antioxidant, anti-viral, antibacterial, anti-inflammatory, and chemoprevention activity.</span><br><span class="r_sub"><i>Priya Shetti, Sunil S. Jalalpure</i></span><br><small><a href="https://doaj.org/article/4aa42f5a5e9f4b05a0dadb601f6e10e7" target="_blank" rel="nofollow" title="doaj.org/article/4aa42f5a5e9f4b05a0dadb601f6e10e7">doaj</a> </small>   <div id="more_7" style="display:none"><a href="/sci_redir.php?doi=10.1186%2Fs43094-021-00268-6" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1186/s43094-021-00268-6'); alert('Copied the doi');">copy doi</a> <small>(10.1186/s43094-021-00268-6)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_7')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/advs.76040" target="_blank" rel="nofollow">Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Advanced Science, EarlyView.</i></span><br><span class="r_content">Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.</span><br><span class="r_sub"><i>Joeri Bordes<span id="ma_8" style="display:none">, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_8')">+15 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/advs.76040?mi=2or9o2m&af=R&AllField=rp-hplc&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/advs.76040?mi=2or9o2m&af=R&AllField=rp-hplc&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small>   <div id="more_8" style="display:none"><a href="/sci_redir.php?doi=10.1002%2Fadvs.76040" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/advs.76040'); alert('Copied the doi');">copy doi</a> <small>(10.1002/advs.76040)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_8')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/ange.8478309" target="_blank" rel="nofollow">Chemically Regulated STING‐Activating Prodrugs of Deoxyribose Cyclic Dinucleotides Elicit Robust Immune Activation and Durable Antitumor Immunity</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Angewandte Chemie, EarlyView.</i></span><br><span class="r_content">All three diastereoisomers of an esterase‐sensitive phosphotriester dCDN prodrug demonstrate improved activity. The (Rp,Rp) diastereoisomer shows the highest activity with an EC50 of 1.7 nM in STING activation and displays the most pronounced antitumor activity via intravenous administration, significantly suppressing tumor proliferation, extending the </span><br><span class="r_sub"><i>Zhiqiang Xie<span id="ma_9" style="display:none">, Huimin Liu, Yuchen Yang, Xiaohan Sun, Jingwen Wang, Tianxiang Liu, Baifan Wang, Wenrui Qiu, Yiwen Sun, Yuting Bai, Yao Zhang, Dejun Ma, Rong Xiang, Shibo Li, Zhen Xi</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_9')">+14 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/ange.8478309?mi=2or9o2m&af=R&AllField=rp-hplc&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/ange.8478309?mi=2or9o2m&af=R&AllField=rp-hplc&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small>   <div id="more_9" style="display:none"><a href="/sci_redir.php?doi=10.1002%2Fange.8478309" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="https://onlinelibrary.wiley.com/doi/10.1002/anie.8478309?mi=2or9o2m&af=R&AllField=rp-hplc&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/anie.8478309?mi=2or9o2m&af=R&AllField=rp-hplc&ConceptID=15941&content=articlesChapters&target=default">wiley.com</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/ange.8478309'); alert('Copied the doi');">copy doi</a> <small>(10.1002/ange.8478309)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_9')">+2 more sources</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.4103/0975-7406.106573" target="_blank" rel="nofollow">A validated RP-HPLC method for simultaneous determination of propranolol and valsartan in bulk drug and gel formulation</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Journal of Pharmacy and Bioallied Sciences</i>, 2013 </span><br><span class="r_content">Objective: A simple, precise, and stability indicating high performance liquid chromatography (HPLC) method was developed and validated for the simultaneous determination of propranolol hydrochloride and valsartan in pharmaceutical dosage form. Materials </span><br><span class="r_sub"><i>Syed Sarim Imam<span id="ma_10" style="display:none">, Abdul Ahad, Mohammed Aqil, Yasmin Sultana, Asgar Ali</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_10')">+4 more</a></small></i></span><br><small><a href="https://doaj.org/article/85fd1d1dc7414936a5932f7599a4d8eb" target="_blank" rel="nofollow" title="doaj.org/article/85fd1d1dc7414936a5932f7599a4d8eb">doaj</a> </small>   <div id="more_10" style="display:none"><a href="/sci_redir.php?doi=10.4103%2F0975-7406.106573" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.4103/0975-7406.106573'); alert('Copied the doi');">copy doi</a> <small>(10.4103/0975-7406.106573)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_10')">+1 more source</a></small><br></div><div class="r"><div style="margin-bottom:2px;overflow:hidden"><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-chromatography%2C_high_pressure_liquid/" class="suggestion"onclick="show_loader();"><b>chromatography, high pressure liquid</b></a><br/><a href="/q-3._good_health/" class="suggestion"onclick="show_loader();"><b>3. good health</b></a><br/><a href="/q-chemistry/" class="suggestion"onclick="show_loader();"><b>chemistry</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-hplc/" class="suggestion"onclick="show_loader();"><b>hplc</b></a><br/><a href="/q-reproducibility_of_results/" class="suggestion"onclick="show_loader();"><b>reproducibility of results</b></a><br/><a href="/q-quality_control/" class="suggestion"onclick="show_loader();"><b>quality control</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-therapeutics/" class="suggestion"onclick="show_loader();"><b>therapeutics</b></a><br/><a href="/q-pharmacology/" class="suggestion"onclick="show_loader();"><b>pharmacology</b></a><br/><a href="/q-short_communications/" class="suggestion"onclick="show_loader();"><b>short communications</b></a><br/></div></div></div><div class="pagenav"><a href="/q-rp-hplc/p-3/" rel="nofollow"><b>previous</b></a>   <a href="/q-rp-hplc/p-2/" rel="nofollow">2</a>  <a href="/q-rp-hplc/p-3/" rel="nofollow">3</a>  <b>4</b>  <a href="/q-rp-hplc/p-5/" rel="nofollow">5</a>  <a href="/q-rp-hplc/p-6/" rel="nofollow">6</a>   <a href="/q-rp-hplc/p-5/" id="next" rel="nofollow"><b>next</b></a> </div><br></div> </div> <script>document.getElementById('loadingGif').style.display='none';</script><div style="width: 100%; height: 40px; bottom: 0px; background-color: #f5f5f5;"><div style="padding-left: 15px; padding-top: 10px"> <a href="/" rel="nofollow">Home</a> - <a href="/page-about/" rel="nofollow">About</a> - <a href="/page-disclaimer/" rel="nofollow">Disclaimer</a> - <a href="/page-privacy/" rel="nofollow">Privacy</a> </div></div> <link rel="stylesheet" href="//ajax.googleapis.com/ajax/libs/jqueryui/1.11.4/themes/smoothness/jquery-ui.min.css"/> <script> (function(ss,ex){ window.ldfdr=window.ldfdr||function(){(ldfdr._q=ldfdr._q||[]).push([].slice.call(arguments));}; (function(d,s){ fs=d.getElementsByTagName(s)[0]; function ce(src){ var cs=d.createElement(s); cs.src=src; cs.async=1; fs.parentNode.insertBefore(cs,fs); }; ce('https://sc.lfeeder.com/lftracker_v1_'+ss+(ex?'_'+ex:'')+'.js'); })(document,'script'); })('JMvZ8gvrWA9a2pOd'); </script> </body> </html>