Results 101 to 110 of about 208,874 (328)

Elastic Taping’s Effect on Exercise Capacity in Recreational Runner with Inspiratory Muscle Training

Surabaya Physical Medicine and Rehabilitation Journal, 2019
Background: Running is a new trend of recreational sports in Indonesia. About 70% of recreational runners have difficulty in improving exercise capacity due to exercise-related transient abdominal pain (ETAP), caused by fatigue of the diaphragmatic ...
Asriningrum Asriningrum, Andriati Andriati, Dewi Poerwandari, Soenarnatalina   +3 more
doaj   +1 more source

Customized strategies for high-yield purification of retinal pigment epithelial cells differentiated from different stem cell sources

Scientific Reports, 2022
Retinal pigment epithelial (RPE) cell dysfunction and death are characteristics of age-related macular degeneration. A promising therapeutic option is RPE cell transplantation.
Kakkad Regha, Mayuri Bhargava, Abdurrahmaan Al-Mubaarak, Chou Chai, Bhav Harshad Parikh, Zengping Liu, Claudine See Wei Wong, Walter Hunziker, Kah Leong Lim, Xinyi Su   +9 more
doaj   +1 more source

Long-Term Efficacy of GMP Grade Xeno-Free hESC-Derived RPE Cells Following Transplantation

Translational Vision Science & Technology, 2017
Purpose Retinal pigment epithelium (RPE) dysfunction underlies the retinal degenerative process in age-related macular degeneration (AMD), and thus RPE cell replacement provides an optimal treatment target. We characterized longitudinally the efficacy of
T. Mcgill, O. Bohana‐Kashtan, Jonathan Stoddard, Michael D. Andrews, Neelay Pandit, Lior R. Rosenberg-Belmaker, O. Wiser, Limor Matzrafi, E. Banin, B. Reubinoff, N. Netzer, C. Irving   +11 more
semanticscholar   +1 more source

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, EarlyView.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source

Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity

Advanced Science, EarlyView.
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu, Ju‐Chan Park, Heesoo Uhm, Yong‐Woo Kim, Hyeon Woo Im, Sangsu Bae   +5 more
wiley   +1 more source

Implications of a twelve-week aerobic exercise on functional work capacity in HIV positive clients on antiretroviral therapy

Turkish Journal of Kinesiology
The implications of aerobic exercise on functional work capacity of Human Immunodeficiency Virus (HIV) positive clients on antiretroviral therapy (ART) in Uganda have been established.
Mwebaze Nicholas, Mshilla Maghanga, Edward Ojuka, Constance A.n. Nsibambi   +3 more
doaj   +1 more source

Predicting ratings of perceived exertion in Australian football players: methods for live estimation

International Journal of Computer Science in Sport, 2016
The ability of machine learning techniques to predict athlete ratings of perceived exertion (RPE) was investigated in professional Australian football players.
Carey D. L., Ong K., Morris M. E., Crow J., Crossley K. M.   +4 more
doaj   +1 more source

Rapid generation of purified human RPE from pluripotent stem cells using 2D cultures and lipoprotein uptake-based sorting

Stem Cell Research & Therapy, 2020
Background Despite increasing demand, current protocols for human pluripotent stem cell (hPSC)-derived retinal pigment epithelium (RPE) remain time, labor, and cost intensive.
Fabio Michelet, Aishwarya Balasankar, Nickolas Teo, Lawrence W. Stanton, Shweta Singhal   +4 more
doaj   +1 more source

Sphingolipids as emerging mediators in retina degeneration [PDF]

, 2019
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber, Rotstein, Nora Patricia, Simon, Maria Victoria, Vera, Marcela Sonia   +3 more
core   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source