Results 101 to 110 of about 174,858 (286)
PLoS ONE, 2012 Retinal pigment epithelium (RPE) cells can be obtained through in vitro differentiation of both embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs).
Ganlu Hu +14 more
doaj +1 more source
Single-channel recordings from cultured human retinal pigment epithelial cells. [PDF]
, 1988 We have applied patch-clamp techniques to on-cell and excised-membrane patches from human retinal pigment epithelial cells in tissue culture. Single-channel currents from at least four ion channel types were observed: three or more potassium-selective ...
Fain, GL, Fox, JA, Pfeffer, BA
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Macromolecular Rapid Communications, EarlyView.Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani +6 more
wiley +1 more source
Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation.
PLoS Genetics, 2019 The retinal pigment epithelium (RPE) is a specialized monolayer of pigmented cells within the eye that is critical for maintaining visual system function.
Nicholas J Hanovice +10 more
doaj +1 more source
Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease
Neuroprotection, EarlyView.Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García +7 more
wiley +1 more source
Understanding RPE Lipofuscin [PDF]
Investigative Opthalmology & Visual Science, 2013 Janet R, Sparrow +2 more
openaire +2 more sources
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas +3 more
wiley +1 more source
Pest Management Science, EarlyView.This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King +6 more
wiley +1 more source
Pest Management Science, EarlyView.This study provides evidence that the timing of co‐inoculation of Leptosphaeria maculans and Leptosphaeria biglobosa determine the outcome of interspecific competition and disease development on their host oilseed rape. Abstract BACKGROUND Phoma stem canker is one of the most economically damaging diseases of oilseed rape, caused by co‐existing fungal ...
Evren Bingol +5 more
wiley +1 more source
Labour Incentive Schemes in a Cournot Duopoly with Simple Institutional Constraints [PDF]
This paper studies equilibrium incentive contracts in a Cournot duopoly, in which institutional arrangements constrain firms to pay (risk-neutral) workers a given salary. In this context, performance-related-pay (PRP) and relative performance evaluation (
Luciano Fanti, Nicola Meccheri
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