Results 41 to 50 of about 2,173 (169)
A numerical method is used to solve the thermal analysis of natural convection in enclosures. This paper proposes the use of an implicit artificial-compressibility model in conjunction with the Radial Point Interpolation Meshless (RPIM) method to mimic ...
Pranowo +2 more
doaj +1 more source
An efficient RPIM for simulating wave motions in saturated porous media
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Chen, S. L., Li, Y. X.
openaire +1 more source
Experience with the Jungfrau‐1M detector at Diamond Light Source
A Jungfrau‐1M integrating detector was characterized at Diamond Light Source and found to be effective for recording macromolecular crystallography diffraction patterns. Parameters for operation and data collection were explored and characterized. The Diamond facility will be upgraded and integrating detectors, such as Jungfrau, will be used more ...
John Matheson +20 more
wiley +1 more source
El problema de Kirsch publicado en 1898, es utilizado como base para corroborar la precisión relativa de los métodos numéricos desarrollados en la mecánica de sólidos.
Fabio H Realpe +3 more
doaj +1 more source
Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong +21 more
wiley +1 more source
Mesh-free kinematic shakedown analysis of cohesive soils
A novel mesh-free solution is proposed for kinematic shakedown analysis of cohesive soils under repeating loads. For this purpose, the continuous velocity field in the mathematical expression of Koiter’s theorem is discretized by the Radial Point ...
Z. Nosrati, S. M. Binesh
doaj +1 more source
Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao +8 more
wiley +1 more source
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper +6 more
wiley +1 more source
Structural and functional specialization of Bordetella pertussis DsbA for pertussis toxin folding
Abstract Disulphide bonds (Dsbs) are essential for the folding, stability, and function of many secreted and membrane‐associated proteins in bacteria. In Gram‐negative species, these bonds are introduced by the Dsb enzyme family, with DsbA acting as the primary thiol oxidase.
Stephanie Penning +9 more
wiley +1 more source
Inhibition of angiotensin I‐converting enzyme is an effective strategy for the treatment of hypertension. However, the clinically available ACE inhibitors cause side effects due to nonselective inhibition of the two catalytic domains of ACE (nACE and cACE).
Kyle S. Gregory +3 more
wiley +1 more source

