Results 41 to 50 of about 5,505 (142)
Advanced Science, Volume 12, Issue 45, December 4, 2025.Discover how Gram‐negative bacteria develop resistance to reactive oxygen species, and how scientists aim to overcome this challenge. Abstract Reactive oxygen species (ROS) are a promising alternative bactericide. However, it is questioned that bacteria can potentially develop resistance to ROS, similar to their resistance against antibiotics and ...
Congyang Mao +9 more
wiley +1 more source
Methylation status of Dnmt1 promoter depends on poly(ADP-ribosy)lation [PDF]
, 2007 Research is focused on CpG islands and on the mechanism that poly(ADP-ribosyl)ation uses to defend the unmethylated state of these important DNA sequences which are located in the promoter regions of the housekeeping genes having a role of transcription ...
Zampieri, Michele
core +1 more source
Clinical and Translational Discovery, Volume 5, Issue 6, December 2025.Gastric precancerous lesions undergo dynamic epigenetic alterations—including DNA methylation, 5‐hydroxymethylcytosine, non‐coding RNAs, and RNA editing—throughout the Correa's cascade. The integration of these multi‐omics epigenetic signatures facilitates non‐invasive risk stratification, which guides personalised surveillance strategy and targeted ...
Kewei Ma +4 more
wiley +1 more source
A Support Vector Machine Base Model for Predicting Heparin-Binding Proteins Using Biological Metrics and XB Patterns as Features [PDF]
, 2016 Heparin is a highly sulphated and negatively charged polysaccharides belonging to the glycosamino- glycans(GAGs) family. It is widely used in medical treatments as an injectable anticoagulant.
Sirrianni, Joseph W
core +1 more source
Alteration of Epigenetic Regulation by Long Noncoding RNAs in Cancer [PDF]
, 2018 Long noncoding RNAs (lncRNAs) are important regulators of the epigenetic status of the human genome. Besides their participation to normal physiology, lncRNA expression and function have been already associated to many diseases, including cancer.
Fatica, Alessandro, Morlando, Mariangela
core +2 more sources
MedComm, Volume 6, Issue 12, December 2025.Radiation‐induced biological effects are an extremely complex and extensive mechanism that involves multiple aspects of physiological activities in organisms. In the medical field, utilizing the damaging effects of radiation to treat tumors is a commonly employed therapeutic approach.
Zhihe Hu +5 more
wiley +1 more source
Epigenetic regulation modulates seasonal temperature‐dependent growth of soybean in southern China
Plant Biotechnology Journal, Volume 23, Issue 10, Page 4580-4601, October 2025.Summary Epigenetic variations, including DNA methylation and small RNAs, are crucial for plant stress adaptation. However, their association with soybean adaptation to natural environments remains unclear. Through multi‐omics analyses, we investigate soybeans from distinct geographical regions (Northern China: HH43, Southern China: HX3, and Wm82) and ...
Yuan Fang +9 more
wiley +1 more source
Evolutionary Origins of Two-Barrel RNA Polymerases and Site-Specific Transcription Initiation [PDF]
, 2017 Evolutionary-related multisubunit RNA polymerases (RNAPs) carry out RNA synthesis in all domains life. Although their catalytic cores and fundamental mechanisms of transcription elongation are conserved, the initiation stage of the transcription cycle ...
Blombach, F, Fouqueau, T, Werner, F
core +1 more source
Advanced Science, Volume 12, Issue 35, September 18, 2025.This study extensively characterizes the B cell response of rainbow trout (Oncorhynchus mykiss) in response to red mark syndrome (RMS). This disease, suspected to be caused by a Midichloria‐like organism (MLO), induces skin lesions in the infected animals, characterized by a massive influx of IgM+ B cells.
J Germán Herranz‐Jusdado +10 more
wiley +1 more source
The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer [PDF]
, 2015 RNA-binding proteins (RBPs) are increasingly identified as post-transcriptional drivers of cancer progression. The RBP LARP1 is an mRNA stability regulator, and elevated expression of the protein in hepatocellular and lung cancers is correlated with ...
Blagden, S +3 more
core +1 more source