Results 231 to 240 of about 2,171,089 (338)

Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery

Advanced Healthcare Materials, EarlyView.
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang, Yue Hui, Zichao Guo, Dawei Liu, Yun Liu, Huajian Gao, Chun‐Xia Zhao   +6 more
wiley   +1 more source

One-Step Multiplex RT-PCR Method for Detection of Melon Viruses. [PDF]

Microorganisms
Han S, Zhou T, Zhang F, Feng J, Han C, Maimaiti Y.   +5 more
europepmc   +1 more source

DEVELOPMENT OF URINE RT-QUANTITATIVE-PCR FOR THE MOLECULAR DIAGNOSIS OF ACUTE REJECTION OF HUMAN RENAL ALLOGRAFTS

, 1999
B Li, Choli Hartono, Rui Ding, Vijay K. Sharma, Janet Mouradian, Manikkam Suthanthiran   +5 more
openalex   +1 more source

3D‐Printed Multidimensional Bionic Mg‐MC/PLGA Composite for Tailored Repair of Segmental Long Bone Defects

Advanced Healthcare Materials, EarlyView.
This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu, Shuai Zhou, Tingting Zou, Guangzhao Hou, Qian Xiao, Lin Li, Jianjun Yang, Wei Chen, Yingze Zhang, Hongzhi Lv   +9 more
wiley   +1 more source

Quantitative Real-Time RT-PCR Verifying Gene Expression Profile of Cavitations Within Human Jaw Bone. [PDF]

Biomedicines
Ghanaati S, Dohle E, Schick F, Lechner J.   +3 more
europepmc   +1 more source

Characterisation of the capsid protein gene from a nodavirus strain affecting the Atlantic halibut Hippoglossus hippoglossus and design of an optimal reverse-transcriptase polymerase chain reaction (RT-PCR) detection assay [PDF]

, 2000
Sindre Grotmol, AH Nerland, Eirik Biering, GK Totland, Tatsuo NISHIZAWA   +4 more
openalex   +1 more source

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

Development of a triplex crystal digital RT-PCR for the detection of PHEV, PRV, and CSFV. [PDF]

Front Vet Sci
Shi K, Hu X, Yin Y, Shi Y, Pan Y, Long F, Feng S, Li Z.   +7 more
europepmc   +1 more source

Detection of Circulating Cancer Cells by RT-PCR in Patients with Resectable Lung Cancer.

, 1995
Hideoki Yokouchi, Osamu Doi, Masahiko Higashiyama, Ken Kodama   +3 more
openalex   +2 more sources

Porous Decellularized Nerve Grafts Facilitate Recellularization and Nerve Regeneration in a Rat Model of Critical Long‐Gap Peripheral Nerve Injury

Advanced Healthcare Materials, EarlyView.
A decellularized nerve graft (DNG) is modified to generate a porous DNG (PDNG). The PDNG is used to repair a 30‐mm peripheral nerve injury (PNI) defect, and is compared with isograft, serving as the standard, and DNG, a widely used alternative. The result shows that PDNG facilitated nerve regeneration in long‐gap PNI, evidenced by better‐aligned axonal
Olawale Alimi Alimi, Mitchell Kuss, Wen Xue, Bo Liu, Mena Asha Krishnan, Tianshu Pan, Zhi He, Han‐Jun Wang, Yuguo Lei, Kai Yang, Bin Duan   +10 more
wiley   +1 more source